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By integrating single-cell RNA-seq and bulk RNA-seq in sphingolipid metabolism, CACYBP was identified as a potential therapeutic target in lung adenocarcinoma

BACKGROUND: Lung adenocarcinoma (LUAD) is a heterogeneous disease with a dismal prognosis for advanced tumors. Immune-associated cells in the microenvironment substantially impact LUAD formation and progression, which has gained increased attention in recent decades. Sphingolipids have a profound im...

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Detalles Bibliográficos
Autores principales:	Zhang, Pengpeng, Pei, Shengbin, Gong, Zeitian, Feng, Yanlong, Zhang, Xiao, Yang, Fang, Wang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914178/ https://www.ncbi.nlm.nih.gov/pubmed/36776843 http://dx.doi.org/10.3389/fimmu.2023.1115272

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