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Effect of the Ketone Body, D-β-Hydroxybutyrate, on Sirtuin2-Mediated Regulation of Mitochondrial Quality Control and the Autophagy–Lysosomal Pathway

Mitochondrial activity and quality control are essential for neuronal homeostasis as neurons rely on glucose oxidative metabolism. The ketone body, D-β-hydroxybutyrate (D-BHB), is metabolized to acetyl-CoA in brain mitochondria and used as an energy fuel alternative to glucose. We have previously re...

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Detalles Bibliográficos
Autores principales: Gómora-García, Juan Carlos, Montiel, Teresa, Hüttenrauch, Melanie, Salcido-Gómez, Ashley, García-Velázquez, Lizbeth, Ramiro-Cortés, Yazmin, Gomora, Juan Carlos, Castro-Obregón, Susana, Massieu, Lourdes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914182/
https://www.ncbi.nlm.nih.gov/pubmed/36766827
http://dx.doi.org/10.3390/cells12030486