Primary Effusion Lymphoma: A Rare and Challenging Diagnosis for Recurrent Pleural Effusion

Primary Effusion Lymphoma is an extremely rare and aggressive subtype of B-cell lymphoma, accounting for only <1% of all cases of this neoplasm. It has a unique clinical presentation because it has a predilection for appearing in body cavities, such as the pleural space, pericardium and peritoneu...

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Detalles Bibliográficos
Autores principales: Pereira, Letícia Jacome, Mohrbacher, Sara, Neves, Precil Diego Miranda de Menezes, Zacchi, Flavia Fernandes Silva, Medeiros, Ivan Ucella Dantas, Sato, Victor Augusto Hamamoto, Oliveira, Érico Souza, Pereira, Leonardo Victor Barbosa, Cuvello-Neto, Américo Lourenço, Baiocchi, Otávio, Chocair, Pedro Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914331/
https://www.ncbi.nlm.nih.gov/pubmed/36766474
http://dx.doi.org/10.3390/diagnostics13030370
Descripción
Sumario:Primary Effusion Lymphoma is an extremely rare and aggressive subtype of B-cell lymphoma, accounting for only <1% of all cases of this neoplasm. It has a unique clinical presentation because it has a predilection for appearing in body cavities, such as the pleural space, pericardium and peritoneum. It mainly affects immunocompromised individuals and may also affect individuals in the Mediterranean region and in areas endemic for human herpesvirus 8 (HHV-8). Herein, we report the case of an 83-year-old immunocompetent male complaining of coughing, fever and progressive dyspnea for 3 days. His past medical history revealed a recurrent pleural effusion for the last three years, as well as losing weight and malaise. A subsequent investigation revealed a PEL diagnosis of the pleura.

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