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Clinical Low-Dose Photon-Counting CT for the Detection of Urolithiasis: Radiation Dose Reduction Is Possible without Compromising Image Quality

Background: This study evaluated the feasibility of reducing the radiation dose in abdominal imaging of urolithiasis with a clinical photon-counting CT (PCCT) by gradually lowering the image quality level (IQL) without compromising the image quality and diagnostic value. Methods: Ninety-eight PCCT e...

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Autores principales: Niehoff, Julius Henning, Carmichael, Alexandra Fiona, Woeltjen, Matthias Michael, Boriesosdick, Jan, Michael, Arwed Elias, Schmidt, Bernhard, Panknin, Christoph, Flohr, Thomas G., Shahzadi, Iram, Piechota, Hansjuergen, Borggrefe, Jan, Kroeger, Jan Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914353/
https://www.ncbi.nlm.nih.gov/pubmed/36766563
http://dx.doi.org/10.3390/diagnostics13030458
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author Niehoff, Julius Henning
Carmichael, Alexandra Fiona
Woeltjen, Matthias Michael
Boriesosdick, Jan
Michael, Arwed Elias
Schmidt, Bernhard
Panknin, Christoph
Flohr, Thomas G.
Shahzadi, Iram
Piechota, Hansjuergen
Borggrefe, Jan
Kroeger, Jan Robert
author_facet Niehoff, Julius Henning
Carmichael, Alexandra Fiona
Woeltjen, Matthias Michael
Boriesosdick, Jan
Michael, Arwed Elias
Schmidt, Bernhard
Panknin, Christoph
Flohr, Thomas G.
Shahzadi, Iram
Piechota, Hansjuergen
Borggrefe, Jan
Kroeger, Jan Robert
author_sort Niehoff, Julius Henning
collection PubMed
description Background: This study evaluated the feasibility of reducing the radiation dose in abdominal imaging of urolithiasis with a clinical photon-counting CT (PCCT) by gradually lowering the image quality level (IQL) without compromising the image quality and diagnostic value. Methods: Ninety-eight PCCT examinations using either IQL70 (n = 31), IQL60 (n = 31) or IQL50 (n = 36) were retrospectively included. Parameters for the radiation dose and the quantitative image quality were analyzed. Qualitative image quality, presence of urolithiasis and diagnostic confidence were rated. Results: Lowering the IQL from 70 to 50 led to a significant decrease (22.8%) in the size-specific dose estimate (SSDE, IQL70 4.57 ± 0.84 mGy, IQL50 3.53 ± 0.70 mGy, p < 0.001). Simultaneously, lowering the IQL led to a minimal deterioration of the quantitative quality, e.g., image noise increased from 9.13 ± 1.99 (IQL70) to 9.91 ± 1.77 (IQL50, p = 0.248). Radiologists did not notice major changes in the image quality throughout the IQLs. Detection rates of urolithiasis (91.3–100%) did not differ markedly. Diagnostic confidence was high and not influenced by the IQL. Conclusions: Adjusting the PCCT scan protocol by lowering the IQL can significantly reduce the radiation dose without significant impairment of the image quality. The detection rate and diagnostic confidence are not impaired by using an ultra-low-dose PCCT scan protocol.
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spelling pubmed-99143532023-02-11 Clinical Low-Dose Photon-Counting CT for the Detection of Urolithiasis: Radiation Dose Reduction Is Possible without Compromising Image Quality Niehoff, Julius Henning Carmichael, Alexandra Fiona Woeltjen, Matthias Michael Boriesosdick, Jan Michael, Arwed Elias Schmidt, Bernhard Panknin, Christoph Flohr, Thomas G. Shahzadi, Iram Piechota, Hansjuergen Borggrefe, Jan Kroeger, Jan Robert Diagnostics (Basel) Article Background: This study evaluated the feasibility of reducing the radiation dose in abdominal imaging of urolithiasis with a clinical photon-counting CT (PCCT) by gradually lowering the image quality level (IQL) without compromising the image quality and diagnostic value. Methods: Ninety-eight PCCT examinations using either IQL70 (n = 31), IQL60 (n = 31) or IQL50 (n = 36) were retrospectively included. Parameters for the radiation dose and the quantitative image quality were analyzed. Qualitative image quality, presence of urolithiasis and diagnostic confidence were rated. Results: Lowering the IQL from 70 to 50 led to a significant decrease (22.8%) in the size-specific dose estimate (SSDE, IQL70 4.57 ± 0.84 mGy, IQL50 3.53 ± 0.70 mGy, p < 0.001). Simultaneously, lowering the IQL led to a minimal deterioration of the quantitative quality, e.g., image noise increased from 9.13 ± 1.99 (IQL70) to 9.91 ± 1.77 (IQL50, p = 0.248). Radiologists did not notice major changes in the image quality throughout the IQLs. Detection rates of urolithiasis (91.3–100%) did not differ markedly. Diagnostic confidence was high and not influenced by the IQL. Conclusions: Adjusting the PCCT scan protocol by lowering the IQL can significantly reduce the radiation dose without significant impairment of the image quality. The detection rate and diagnostic confidence are not impaired by using an ultra-low-dose PCCT scan protocol. MDPI 2023-01-26 /pmc/articles/PMC9914353/ /pubmed/36766563 http://dx.doi.org/10.3390/diagnostics13030458 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Niehoff, Julius Henning
Carmichael, Alexandra Fiona
Woeltjen, Matthias Michael
Boriesosdick, Jan
Michael, Arwed Elias
Schmidt, Bernhard
Panknin, Christoph
Flohr, Thomas G.
Shahzadi, Iram
Piechota, Hansjuergen
Borggrefe, Jan
Kroeger, Jan Robert
Clinical Low-Dose Photon-Counting CT for the Detection of Urolithiasis: Radiation Dose Reduction Is Possible without Compromising Image Quality
title Clinical Low-Dose Photon-Counting CT for the Detection of Urolithiasis: Radiation Dose Reduction Is Possible without Compromising Image Quality
title_full Clinical Low-Dose Photon-Counting CT for the Detection of Urolithiasis: Radiation Dose Reduction Is Possible without Compromising Image Quality
title_fullStr Clinical Low-Dose Photon-Counting CT for the Detection of Urolithiasis: Radiation Dose Reduction Is Possible without Compromising Image Quality
title_full_unstemmed Clinical Low-Dose Photon-Counting CT for the Detection of Urolithiasis: Radiation Dose Reduction Is Possible without Compromising Image Quality
title_short Clinical Low-Dose Photon-Counting CT for the Detection of Urolithiasis: Radiation Dose Reduction Is Possible without Compromising Image Quality
title_sort clinical low-dose photon-counting ct for the detection of urolithiasis: radiation dose reduction is possible without compromising image quality
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914353/
https://www.ncbi.nlm.nih.gov/pubmed/36766563
http://dx.doi.org/10.3390/diagnostics13030458
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