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Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases

Candida auris is considered to be an emerging fungal pathogen and is related to high mortality rates, persistent candidemia, inconsistencies in susceptibility testing results and misidentification by available commercial identification systems. Multidrug-resistant (MDR) and pandrug-resistant (PDR) s...

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Autores principales: Geremia, Nicholas, Brugnaro, Pierluigi, Solinas, Maria, Scarparo, Claudio, Panese, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914380/
https://www.ncbi.nlm.nih.gov/pubmed/36767000
http://dx.doi.org/10.3390/healthcare11030425
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author Geremia, Nicholas
Brugnaro, Pierluigi
Solinas, Maria
Scarparo, Claudio
Panese, Sandro
author_facet Geremia, Nicholas
Brugnaro, Pierluigi
Solinas, Maria
Scarparo, Claudio
Panese, Sandro
author_sort Geremia, Nicholas
collection PubMed
description Candida auris is considered to be an emerging fungal pathogen and is related to high mortality rates, persistent candidemia, inconsistencies in susceptibility testing results and misidentification by available commercial identification systems. Multidrug-resistant (MDR) and pandrug-resistant (PDR) strains are increasingly detected. In Europe, hospital outbreaks caused by C. auris have been reported in the United Kingdom (UK), Italy and Spain; however, several cases have been sporadically detected in all European countries. C. auris is difficult to control despite enhanced control measures due to its ability to survive for a long time in environments and colonize patients for prolonged periods. An adequate laboratory diagnostic capacity and national surveillance are fundamental to rapidly detect new C. auris cases and to apply the correct measures to circumscribe them and prevent their spread. Our narrative review aims to highlight the primary C. auris outbreaks and case reports that have occurred in Europe.
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spelling pubmed-99143802023-02-11 Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases Geremia, Nicholas Brugnaro, Pierluigi Solinas, Maria Scarparo, Claudio Panese, Sandro Healthcare (Basel) Review Candida auris is considered to be an emerging fungal pathogen and is related to high mortality rates, persistent candidemia, inconsistencies in susceptibility testing results and misidentification by available commercial identification systems. Multidrug-resistant (MDR) and pandrug-resistant (PDR) strains are increasingly detected. In Europe, hospital outbreaks caused by C. auris have been reported in the United Kingdom (UK), Italy and Spain; however, several cases have been sporadically detected in all European countries. C. auris is difficult to control despite enhanced control measures due to its ability to survive for a long time in environments and colonize patients for prolonged periods. An adequate laboratory diagnostic capacity and national surveillance are fundamental to rapidly detect new C. auris cases and to apply the correct measures to circumscribe them and prevent their spread. Our narrative review aims to highlight the primary C. auris outbreaks and case reports that have occurred in Europe. MDPI 2023-02-02 /pmc/articles/PMC9914380/ /pubmed/36767000 http://dx.doi.org/10.3390/healthcare11030425 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Geremia, Nicholas
Brugnaro, Pierluigi
Solinas, Maria
Scarparo, Claudio
Panese, Sandro
Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases
title Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases
title_full Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases
title_fullStr Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases
title_full_unstemmed Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases
title_short Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases
title_sort candida auris as an emergent public health problem: a current update on european outbreaks and cases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914380/
https://www.ncbi.nlm.nih.gov/pubmed/36767000
http://dx.doi.org/10.3390/healthcare11030425
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