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Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases
Candida auris is considered to be an emerging fungal pathogen and is related to high mortality rates, persistent candidemia, inconsistencies in susceptibility testing results and misidentification by available commercial identification systems. Multidrug-resistant (MDR) and pandrug-resistant (PDR) s...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914380/ https://www.ncbi.nlm.nih.gov/pubmed/36767000 http://dx.doi.org/10.3390/healthcare11030425 |
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author | Geremia, Nicholas Brugnaro, Pierluigi Solinas, Maria Scarparo, Claudio Panese, Sandro |
author_facet | Geremia, Nicholas Brugnaro, Pierluigi Solinas, Maria Scarparo, Claudio Panese, Sandro |
author_sort | Geremia, Nicholas |
collection | PubMed |
description | Candida auris is considered to be an emerging fungal pathogen and is related to high mortality rates, persistent candidemia, inconsistencies in susceptibility testing results and misidentification by available commercial identification systems. Multidrug-resistant (MDR) and pandrug-resistant (PDR) strains are increasingly detected. In Europe, hospital outbreaks caused by C. auris have been reported in the United Kingdom (UK), Italy and Spain; however, several cases have been sporadically detected in all European countries. C. auris is difficult to control despite enhanced control measures due to its ability to survive for a long time in environments and colonize patients for prolonged periods. An adequate laboratory diagnostic capacity and national surveillance are fundamental to rapidly detect new C. auris cases and to apply the correct measures to circumscribe them and prevent their spread. Our narrative review aims to highlight the primary C. auris outbreaks and case reports that have occurred in Europe. |
format | Online Article Text |
id | pubmed-9914380 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99143802023-02-11 Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases Geremia, Nicholas Brugnaro, Pierluigi Solinas, Maria Scarparo, Claudio Panese, Sandro Healthcare (Basel) Review Candida auris is considered to be an emerging fungal pathogen and is related to high mortality rates, persistent candidemia, inconsistencies in susceptibility testing results and misidentification by available commercial identification systems. Multidrug-resistant (MDR) and pandrug-resistant (PDR) strains are increasingly detected. In Europe, hospital outbreaks caused by C. auris have been reported in the United Kingdom (UK), Italy and Spain; however, several cases have been sporadically detected in all European countries. C. auris is difficult to control despite enhanced control measures due to its ability to survive for a long time in environments and colonize patients for prolonged periods. An adequate laboratory diagnostic capacity and national surveillance are fundamental to rapidly detect new C. auris cases and to apply the correct measures to circumscribe them and prevent their spread. Our narrative review aims to highlight the primary C. auris outbreaks and case reports that have occurred in Europe. MDPI 2023-02-02 /pmc/articles/PMC9914380/ /pubmed/36767000 http://dx.doi.org/10.3390/healthcare11030425 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Geremia, Nicholas Brugnaro, Pierluigi Solinas, Maria Scarparo, Claudio Panese, Sandro Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases |
title | Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases |
title_full | Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases |
title_fullStr | Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases |
title_full_unstemmed | Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases |
title_short | Candida auris as an Emergent Public Health Problem: A Current Update on European Outbreaks and Cases |
title_sort | candida auris as an emergent public health problem: a current update on european outbreaks and cases |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914380/ https://www.ncbi.nlm.nih.gov/pubmed/36767000 http://dx.doi.org/10.3390/healthcare11030425 |
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