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The Association between Admission Serum Phosphorus and Preoperative Deep Venous Thrombosis in Geriatric Hip Fracture: A Retrospective Study

Objective: This study aimed to evaluate the association between serum phosphorus level and preoperative deep vein thrombosis (DVT) in geriatric hip fractures. Methods: Older adults with hip fractures were screened between January 2015 and September 2019. Demographic and clinical characteristics of t...

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Autores principales: Lu, Dong-Xing, Zhang, Kun, Ma, Teng, Li, Ming, Li, Zhong, Xu, Yi-Bo, Wang, Chao-Feng, Ren, Cheng, Zhang, Bin-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914597/
https://www.ncbi.nlm.nih.gov/pubmed/36766651
http://dx.doi.org/10.3390/diagnostics13030545
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author Lu, Dong-Xing
Zhang, Kun
Ma, Teng
Li, Ming
Li, Zhong
Xu, Yi-Bo
Wang, Chao-Feng
Ren, Cheng
Zhang, Bin-Fei
author_facet Lu, Dong-Xing
Zhang, Kun
Ma, Teng
Li, Ming
Li, Zhong
Xu, Yi-Bo
Wang, Chao-Feng
Ren, Cheng
Zhang, Bin-Fei
author_sort Lu, Dong-Xing
collection PubMed
description Objective: This study aimed to evaluate the association between serum phosphorus level and preoperative deep vein thrombosis (DVT) in geriatric hip fractures. Methods: Older adults with hip fractures were screened between January 2015 and September 2019. Demographic and clinical characteristics of the patients were collected. Multivariate binary logistic regression and generalized additive models were used to identify the linear and nonlinear associations between serum phosphorus levels and preoperative DVT. Analyses were performed using Empower Stats and R software. Results: In this study, 1818 patients were included, with an average age of 79.39 ± 6.87. Of these, 30.25% were males, and 580 patients had DVT. The study found that when serum phosphorus was used as a continuous variable, there was a statistically significant difference in the relationship between blood phosphorus and the occurrence of DVT (p < 0.05). Furthermore, we also found curvilinear relationships. Serum phosphorus = 0.71 mmol/L was the inflection point in the curve. When serum phosphorus was <0.71 mmol/L, the serum phosphorus was associated with DVT (OR = 1.64; 95% CI: 1.04–2.59; p = 0.0333). With a 0.1 mmol/L increase, the DVT increased 0.64 times. When phosphorus was >0.71 mmol/L, there was no significant difference in the correlation between serum phosphorus levels and DVT (OR = 1.03; 95% CI: 0.98–1.09; p = 0.186). Conclusion: Serum phosphorus was nonlinearly associated with preoperative DVT in geriatric patients with hip fractures, and serum phosphorus level could be considered a predictor of DVT risk.
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spelling pubmed-99145972023-02-11 The Association between Admission Serum Phosphorus and Preoperative Deep Venous Thrombosis in Geriatric Hip Fracture: A Retrospective Study Lu, Dong-Xing Zhang, Kun Ma, Teng Li, Ming Li, Zhong Xu, Yi-Bo Wang, Chao-Feng Ren, Cheng Zhang, Bin-Fei Diagnostics (Basel) Article Objective: This study aimed to evaluate the association between serum phosphorus level and preoperative deep vein thrombosis (DVT) in geriatric hip fractures. Methods: Older adults with hip fractures were screened between January 2015 and September 2019. Demographic and clinical characteristics of the patients were collected. Multivariate binary logistic regression and generalized additive models were used to identify the linear and nonlinear associations between serum phosphorus levels and preoperative DVT. Analyses were performed using Empower Stats and R software. Results: In this study, 1818 patients were included, with an average age of 79.39 ± 6.87. Of these, 30.25% were males, and 580 patients had DVT. The study found that when serum phosphorus was used as a continuous variable, there was a statistically significant difference in the relationship between blood phosphorus and the occurrence of DVT (p < 0.05). Furthermore, we also found curvilinear relationships. Serum phosphorus = 0.71 mmol/L was the inflection point in the curve. When serum phosphorus was <0.71 mmol/L, the serum phosphorus was associated with DVT (OR = 1.64; 95% CI: 1.04–2.59; p = 0.0333). With a 0.1 mmol/L increase, the DVT increased 0.64 times. When phosphorus was >0.71 mmol/L, there was no significant difference in the correlation between serum phosphorus levels and DVT (OR = 1.03; 95% CI: 0.98–1.09; p = 0.186). Conclusion: Serum phosphorus was nonlinearly associated with preoperative DVT in geriatric patients with hip fractures, and serum phosphorus level could be considered a predictor of DVT risk. MDPI 2023-02-02 /pmc/articles/PMC9914597/ /pubmed/36766651 http://dx.doi.org/10.3390/diagnostics13030545 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lu, Dong-Xing
Zhang, Kun
Ma, Teng
Li, Ming
Li, Zhong
Xu, Yi-Bo
Wang, Chao-Feng
Ren, Cheng
Zhang, Bin-Fei
The Association between Admission Serum Phosphorus and Preoperative Deep Venous Thrombosis in Geriatric Hip Fracture: A Retrospective Study
title The Association between Admission Serum Phosphorus and Preoperative Deep Venous Thrombosis in Geriatric Hip Fracture: A Retrospective Study
title_full The Association between Admission Serum Phosphorus and Preoperative Deep Venous Thrombosis in Geriatric Hip Fracture: A Retrospective Study
title_fullStr The Association between Admission Serum Phosphorus and Preoperative Deep Venous Thrombosis in Geriatric Hip Fracture: A Retrospective Study
title_full_unstemmed The Association between Admission Serum Phosphorus and Preoperative Deep Venous Thrombosis in Geriatric Hip Fracture: A Retrospective Study
title_short The Association between Admission Serum Phosphorus and Preoperative Deep Venous Thrombosis in Geriatric Hip Fracture: A Retrospective Study
title_sort association between admission serum phosphorus and preoperative deep venous thrombosis in geriatric hip fracture: a retrospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914597/
https://www.ncbi.nlm.nih.gov/pubmed/36766651
http://dx.doi.org/10.3390/diagnostics13030545
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