Incorporation of a TGF-β2-inhibiting oligodeoxynucleotide molecular adjuvant into a tumor cell lysate vaccine to enhance antiglioma immunity in mice

INTRODUCTION: Transforming growth factor β2 (TGF-β2), also known as glioma-derived T-cell suppressor factor, is associated with the impairment of tumor immune surveillance. Therefore, blocking TGF-β2 signaling probably be a feasible strategy to develop a novel type of adjuvant for glioma vaccines to...

Descripción completa

Detalles Bibliográficos
Autores principales: Tu, Liqun, Wang, Zhe, Yang, Lei, Sun, Xiaomeng, Yao, Yunpeng, Zhang, Peng, Zhang, Xiaotian, Wang, Liying, Yu, Yongli, Yang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914600/
https://www.ncbi.nlm.nih.gov/pubmed/36776837
http://dx.doi.org/10.3389/fimmu.2023.1013342

Ejemplares similares

Ejemplares similares