Cargando…

Autophagy Requirements for Eye Lens Differentiation and Transparency

Recent evidence points to autophagy as an essential cellular requirement for achieving the mature structure, homeostasis, and transparency of the lens. Collective evidence from multiple laboratories using chick, mouse, primate, and human model systems provides evidence that classic autophagy structu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brennan, Lisa, Costello, M. Joseph, Hejtmancik, J. Fielding, Menko, A. Sue, Riazuddin, S. Amer, Shiels, Alan, Kantorow, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914699/ https://www.ncbi.nlm.nih.gov/pubmed/36766820 http://dx.doi.org/10.3390/cells12030475

Ejemplares similares

Spatial expression patterns of autophagy genes in the eye lens and induction of autophagy in lens cells
por: Brennan, Lisa Ann, et al.
Publicado: (2012)

Patterns of Crystallin Gene Expression in Differentiation State Specific Regions of the Embryonic Chicken Lens
por: Ma, Zhiwei, et al.
Publicado: (2022)

Changes in DNA methylation hallmark alterations in chromatin accessibility and gene expression for eye lens differentiation
por: Disatham, Joshua, et al.
Publicado: (2022)

Differentiation State-Specific Mitochondrial Dynamic Regulatory Networks Are Revealed by Global Transcriptional Analysis of the Developing Chicken Lens
por: Chauss, Daniel, et al.
Publicado: (2014)

Multiomics Analysis Reveals Novel Genetic Determinants for Lens Differentiation, Structure, and Transparency
por: Disatham, Joshua, et al.
Publicado: (2023)

A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis
por: Disatham, Joshua, et al.
Publicado: (2021)

Identification and Ultrastructural Characterization of a Novel Nuclear Degradation Complex in Differentiating Lens Fiber Cells
por: Costello, M. Joseph, et al.
Publicado: (2016)

TXNL6 Is a Novel Oxidative Stress-Induced Reducing System for Methionine Sulfoxide Reductase A Repair of α-Crystallin and Cytochrome C in the Eye Lens
por: Brennan, Lisa A., et al.
Publicado: (2010)

Germ-line and somatic EPHA2 coding variants in lens aging and cataract
por: Bennett, Thomas M., et al.
Publicado: (2017)

Primary congenital glaucoma localizes to chromosome 14q24.2-24.3 in two consanguineous Pakistani families
por: Firasat, Sabika, et al.
Publicado: (2008)

The involvement of caspases in the process of nuclear removal during lens fiber cell differentiation
por: Gheyas, Rifah, et al.
Publicado: (2023)

Cat-Map: putting cataract on the map
por: Shiels, Alan, et al.
Publicado: (2010)

Novel SIL1 mutations in consanguineous Pakistani families mapping to chromosomes 5q31
por: Riazuddin, S. Amer, et al.
Publicado: (2009)

Suppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cells
por: Basu, Subhasree, et al.
Publicado: (2014)

Autosomal recessive congenital cataracts linked to HSF4 in a consanguineous Pakistani family
por: Jiao, Xiaodong, et al.
Publicado: (2019)

Chromatin features, RNA polymerase II and the comparative expression of lens genes encoding crystallins, transcription factors, and autophagy mediators
por: Sun, Jian, et al.
Publicado: (2015)

Novel mitochondrial derived Nuclear Excisosome degrades nuclei during differentiation of prosimian Galago (bush baby) monkey lenses
por: Costello, M. Joseph, et al.
Publicado: (2020)

Induction of Immune Surveillance of the Dysmorphogenic Lens
por: Logan, Caitlin M., et al.
Publicado: (2017)

Fibrosis: Shared Lessons From the Lens and Cornea
por: Menko, A. Sue, et al.
Publicado: (2019)

Whole genome sequencing data for two individuals of Pakistani descent
por: Khan, Shahid Y., et al.
Publicado: (2018)

Age-related changes in eye lens biomechanics, morphology, refractive index and transparency
por: Cheng, Catherine, et al.
Publicado: (2019)

Insights into the biochemical and biophysical mechanisms mediating the longevity of the transparent optics of the eye lens
por: Quinlan, Roy A., et al.
Publicado: (2022)

Repurposing a Cyclin-Dependent Kinase 1 (CDK1) Mitotic Regulatory Network to Complete Terminal Differentiation in Lens Fiber Cells
por: Taylor, Allen, et al.
Publicado: (2023)

Noncoding variation of the gene for ferritin light chain in hereditary and age-related cataract
por: Bennett, Thomas M., et al.
Publicado: (2013)

Mutations in the β-subunit of rod phosphodiesterase identified in consanguineous Pakistani families with autosomal recessive retinitis pigmentosa
por: Ali, Shahbaz, et al.
Publicado: (2011)

Novel mutations in RPE65 identified in consanguineous Pakistani families with retinal dystrophy
por: Kabir, Firoz, et al.
Publicado: (2013)

A genomic deletion encompassing CRYBB2-CRYBB2P1 is responsible for autosomal recessive congenital cataracts
por: Irum, Bushra, et al.
Publicado: (2022)

The Pro-Fibrotic Response to Lens Injury Is Signaled in a PI3K Isoform-Specific Manner
por: Menko, A. Sue, et al.
Publicado: (2022)

A new locus for autosomal recessive congenital cataract identified in a Pakistani family
por: Kaul, Haiba, et al.
Publicado: (2010)

Melanosomes in pigmented epithelia maintain eye lens transparency during zebrafish embryonic development
por: Takamiya, Masanari, et al.
Publicado: (2016)

Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency
por: Shin, Seula, et al.
Publicado: (2021)

Examining PI3K-signaling-dependent regulation of lens organelle free zone formation via immunolocalization and immunoblotting in chick embryos
por: Gheyas, Rifah, et al.
Publicado: (2023)

Whole genome sequencing data of multiple individuals of Pakistani descent
por: Khan, Shahid Y., et al.
Publicado: (2020)

Autosomal recessive congenital cataract linked to EPHA2 in a consanguineous Pakistani family
por: Kaul, Haiba, et al.
Publicado: (2010)

Resident immune cells of the avascular lens: Mediators of the injury and fibrotic response of the lens
por: Menko, A. Sue, et al.
Publicado: (2021)

A Common Ancestral Mutation in CRYBB3 Identified in Multiple Consanguineous Families with Congenital Cataracts
por: Jiao, Xiaodong, et al.
Publicado: (2016)

Mutations in CERKL and RP1 cause retinitis pigmentosa in Pakistani families
por: Nadeem, Raheela, et al.
Publicado: (2020)

Structural Integrity of the Greek Key Motif in βγ-Crystallins Is Vital for Central Eye Lens Transparency
por: Vendra, Venkata Pulla Rao, et al.
Publicado: (2013)

The function of filensin and phakinin in lens transparency
por: Oka, Mikako, et al.
Publicado: (2008)

AIPL1 implicated in the pathogenesis of two cases of autosomal recessive retinal degeneration
por: Li, David, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_lritk6k8d3e0itoe7fv8m9ul77