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Immunogenomic Biomarkers and Validation in Lynch Syndrome

Lynch syndrome (LS) is an inherited disorder in which affected individuals have a significantly higher-than-average risk of developing colorectal and non-colorectal cancers, often before the age of 50 years. In LS, mutations in DNA repair genes lead to a dysfunctional post-replication repair system....

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Detalles Bibliográficos
Autores principales: Chambuso, Ramadhani, Mthembu, Mbali, Kaambo, Eveline, Robertson, Barbara, Ramesar, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914748/
https://www.ncbi.nlm.nih.gov/pubmed/36766832
http://dx.doi.org/10.3390/cells12030491