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The Efficacy and Safety of the GATT Procedure in Open-Angle Glaucoma—6-Month Results

AIM. The aim of the study was to retrospectively evaluate the efficacy and safety of GATT during a 6-month observation period. MATERIAL AND METHODS. The studied group consisted of 69 open-angle glaucoma patients treated with GATT as the only procedure or in combination with cataract surgery. Patient...

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Autores principales: Ćwiklińska-Haszcz, Agnieszka, Żarnowski, Tomasz, Wróbel-Dudzińska, Dominika, Kosior-Jarecka, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914959/
https://www.ncbi.nlm.nih.gov/pubmed/36768125
http://dx.doi.org/10.3390/ijerph20032759
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author Ćwiklińska-Haszcz, Agnieszka
Żarnowski, Tomasz
Wróbel-Dudzińska, Dominika
Kosior-Jarecka, Ewa
author_facet Ćwiklińska-Haszcz, Agnieszka
Żarnowski, Tomasz
Wróbel-Dudzińska, Dominika
Kosior-Jarecka, Ewa
author_sort Ćwiklińska-Haszcz, Agnieszka
collection PubMed
description AIM. The aim of the study was to retrospectively evaluate the efficacy and safety of GATT during a 6-month observation period. MATERIAL AND METHODS. The studied group consisted of 69 open-angle glaucoma patients treated with GATT as the only procedure or in combination with cataract surgery. Patients were assessed 1 day, 10 days, 1 month, 3 months, and 6 months after the surgery via standard ophthalmic examination including VF, IOP, and BCVA. The number of medications taken daily and possible complications were checked. Two criteria of success were established (S1: IOP decrease by 30% and S2: IOP lower than 18 mm Hg). RESULTS. Before the surgery, the mean IOP was 26.94 mmHg and significantly decreased after GATT to 15.59 mmHg at 6M. BCVA did not significantly differ between the visits. The mean MD did not change significantly within the 6-month observation period (−8.20 dB vs. −8.16 dB, p = 0.9824), similar to the mean VFI (64.31% vs. 63.05%, p = 0.8571). A 30% IOP decrease at 6M visit was obtained in 95.6% of patients, and 37.7% needed medications to stabilize IOP. An IOP lower than 18 mmHg at 6M was obtained in 91.3% of studied patients after the GATT procedure, and in 58.0% without additional medications. The mean number of medications received daily decreased significantly at 6M compared to preoperative results (2.59 at inclusion vs. 0.76 at 6M, p = 0.0004). The most frequent complication after surgery was hyphema, which resolved spontaneously within 10 days. CONCLUSION. The 6-month observation showed that GATT is a minimally invasive glaucoma-surgery technique that enables an effective and safe IOP decrease.
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spelling pubmed-99149592023-02-11 The Efficacy and Safety of the GATT Procedure in Open-Angle Glaucoma—6-Month Results Ćwiklińska-Haszcz, Agnieszka Żarnowski, Tomasz Wróbel-Dudzińska, Dominika Kosior-Jarecka, Ewa Int J Environ Res Public Health Article AIM. The aim of the study was to retrospectively evaluate the efficacy and safety of GATT during a 6-month observation period. MATERIAL AND METHODS. The studied group consisted of 69 open-angle glaucoma patients treated with GATT as the only procedure or in combination with cataract surgery. Patients were assessed 1 day, 10 days, 1 month, 3 months, and 6 months after the surgery via standard ophthalmic examination including VF, IOP, and BCVA. The number of medications taken daily and possible complications were checked. Two criteria of success were established (S1: IOP decrease by 30% and S2: IOP lower than 18 mm Hg). RESULTS. Before the surgery, the mean IOP was 26.94 mmHg and significantly decreased after GATT to 15.59 mmHg at 6M. BCVA did not significantly differ between the visits. The mean MD did not change significantly within the 6-month observation period (−8.20 dB vs. −8.16 dB, p = 0.9824), similar to the mean VFI (64.31% vs. 63.05%, p = 0.8571). A 30% IOP decrease at 6M visit was obtained in 95.6% of patients, and 37.7% needed medications to stabilize IOP. An IOP lower than 18 mmHg at 6M was obtained in 91.3% of studied patients after the GATT procedure, and in 58.0% without additional medications. The mean number of medications received daily decreased significantly at 6M compared to preoperative results (2.59 at inclusion vs. 0.76 at 6M, p = 0.0004). The most frequent complication after surgery was hyphema, which resolved spontaneously within 10 days. CONCLUSION. The 6-month observation showed that GATT is a minimally invasive glaucoma-surgery technique that enables an effective and safe IOP decrease. MDPI 2023-02-03 /pmc/articles/PMC9914959/ /pubmed/36768125 http://dx.doi.org/10.3390/ijerph20032759 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ćwiklińska-Haszcz, Agnieszka
Żarnowski, Tomasz
Wróbel-Dudzińska, Dominika
Kosior-Jarecka, Ewa
The Efficacy and Safety of the GATT Procedure in Open-Angle Glaucoma—6-Month Results
title The Efficacy and Safety of the GATT Procedure in Open-Angle Glaucoma—6-Month Results
title_full The Efficacy and Safety of the GATT Procedure in Open-Angle Glaucoma—6-Month Results
title_fullStr The Efficacy and Safety of the GATT Procedure in Open-Angle Glaucoma—6-Month Results
title_full_unstemmed The Efficacy and Safety of the GATT Procedure in Open-Angle Glaucoma—6-Month Results
title_short The Efficacy and Safety of the GATT Procedure in Open-Angle Glaucoma—6-Month Results
title_sort efficacy and safety of the gatt procedure in open-angle glaucoma—6-month results
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914959/
https://www.ncbi.nlm.nih.gov/pubmed/36768125
http://dx.doi.org/10.3390/ijerph20032759
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