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Analysis of Cannabinoids in Biological Specimens: An Update

Cannabinoids are still the most consumed drugs of abuse worldwide. Despite being considered less harmful to human health, particularly if compared with opiates or cocaine, cannabis consumption has important medico-legal and public health consequences. For this reason, the development and optimizatio...

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Detalles Bibliográficos
Autores principales: Antunes, Mónica, Barroso, Mário, Gallardo, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915035/
https://www.ncbi.nlm.nih.gov/pubmed/36767678
http://dx.doi.org/10.3390/ijerph20032312
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author Antunes, Mónica
Barroso, Mário
Gallardo, Eugenia
author_facet Antunes, Mónica
Barroso, Mário
Gallardo, Eugenia
author_sort Antunes, Mónica
collection PubMed
description Cannabinoids are still the most consumed drugs of abuse worldwide. Despite being considered less harmful to human health, particularly if compared with opiates or cocaine, cannabis consumption has important medico-legal and public health consequences. For this reason, the development and optimization of sensitive analytical methods that allow the determination of these compounds in different biological specimens is important, involving relevant efforts from laboratories. This paper will discuss cannabis consumption; toxicokinetics, the most detected compounds in biological samples; and characteristics of the latter. In addition, a comprehensive review of extraction methods and analytical tools available for cannabinoid detection in selected biological specimens will be reviewed. Important issues such as pitfalls and cut-off values will be considered.
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spelling pubmed-99150352023-02-11 Analysis of Cannabinoids in Biological Specimens: An Update Antunes, Mónica Barroso, Mário Gallardo, Eugenia Int J Environ Res Public Health Review Cannabinoids are still the most consumed drugs of abuse worldwide. Despite being considered less harmful to human health, particularly if compared with opiates or cocaine, cannabis consumption has important medico-legal and public health consequences. For this reason, the development and optimization of sensitive analytical methods that allow the determination of these compounds in different biological specimens is important, involving relevant efforts from laboratories. This paper will discuss cannabis consumption; toxicokinetics, the most detected compounds in biological samples; and characteristics of the latter. In addition, a comprehensive review of extraction methods and analytical tools available for cannabinoid detection in selected biological specimens will be reviewed. Important issues such as pitfalls and cut-off values will be considered. MDPI 2023-01-28 /pmc/articles/PMC9915035/ /pubmed/36767678 http://dx.doi.org/10.3390/ijerph20032312 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Antunes, Mónica
Barroso, Mário
Gallardo, Eugenia
Analysis of Cannabinoids in Biological Specimens: An Update
title Analysis of Cannabinoids in Biological Specimens: An Update
title_full Analysis of Cannabinoids in Biological Specimens: An Update
title_fullStr Analysis of Cannabinoids in Biological Specimens: An Update
title_full_unstemmed Analysis of Cannabinoids in Biological Specimens: An Update
title_short Analysis of Cannabinoids in Biological Specimens: An Update
title_sort analysis of cannabinoids in biological specimens: an update
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915035/
https://www.ncbi.nlm.nih.gov/pubmed/36767678
http://dx.doi.org/10.3390/ijerph20032312
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