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Analysis of Cannabinoids in Biological Specimens: An Update
Cannabinoids are still the most consumed drugs of abuse worldwide. Despite being considered less harmful to human health, particularly if compared with opiates or cocaine, cannabis consumption has important medico-legal and public health consequences. For this reason, the development and optimizatio...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915035/ https://www.ncbi.nlm.nih.gov/pubmed/36767678 http://dx.doi.org/10.3390/ijerph20032312 |
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author | Antunes, Mónica Barroso, Mário Gallardo, Eugenia |
author_facet | Antunes, Mónica Barroso, Mário Gallardo, Eugenia |
author_sort | Antunes, Mónica |
collection | PubMed |
description | Cannabinoids are still the most consumed drugs of abuse worldwide. Despite being considered less harmful to human health, particularly if compared with opiates or cocaine, cannabis consumption has important medico-legal and public health consequences. For this reason, the development and optimization of sensitive analytical methods that allow the determination of these compounds in different biological specimens is important, involving relevant efforts from laboratories. This paper will discuss cannabis consumption; toxicokinetics, the most detected compounds in biological samples; and characteristics of the latter. In addition, a comprehensive review of extraction methods and analytical tools available for cannabinoid detection in selected biological specimens will be reviewed. Important issues such as pitfalls and cut-off values will be considered. |
format | Online Article Text |
id | pubmed-9915035 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99150352023-02-11 Analysis of Cannabinoids in Biological Specimens: An Update Antunes, Mónica Barroso, Mário Gallardo, Eugenia Int J Environ Res Public Health Review Cannabinoids are still the most consumed drugs of abuse worldwide. Despite being considered less harmful to human health, particularly if compared with opiates or cocaine, cannabis consumption has important medico-legal and public health consequences. For this reason, the development and optimization of sensitive analytical methods that allow the determination of these compounds in different biological specimens is important, involving relevant efforts from laboratories. This paper will discuss cannabis consumption; toxicokinetics, the most detected compounds in biological samples; and characteristics of the latter. In addition, a comprehensive review of extraction methods and analytical tools available for cannabinoid detection in selected biological specimens will be reviewed. Important issues such as pitfalls and cut-off values will be considered. MDPI 2023-01-28 /pmc/articles/PMC9915035/ /pubmed/36767678 http://dx.doi.org/10.3390/ijerph20032312 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Antunes, Mónica Barroso, Mário Gallardo, Eugenia Analysis of Cannabinoids in Biological Specimens: An Update |
title | Analysis of Cannabinoids in Biological Specimens: An Update |
title_full | Analysis of Cannabinoids in Biological Specimens: An Update |
title_fullStr | Analysis of Cannabinoids in Biological Specimens: An Update |
title_full_unstemmed | Analysis of Cannabinoids in Biological Specimens: An Update |
title_short | Analysis of Cannabinoids in Biological Specimens: An Update |
title_sort | analysis of cannabinoids in biological specimens: an update |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915035/ https://www.ncbi.nlm.nih.gov/pubmed/36767678 http://dx.doi.org/10.3390/ijerph20032312 |
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