Cargando…

Sustained Cytotoxic Response of Peripheral Blood Mononuclear Cells from Unvaccinated Individuals Admitted to the ICU Due to Critical COVID-19 Is Essential to Avoid a Fatal Outcome

The main objective of this study was to determine the influence of the cytotoxic activity of peripheral blood mononuclear cells (PBMCs) on the outcome of unvaccinated individuals with critical COVID-19 admitted to the ICU. Blood samples from 23 individuals were collected upon admission and then ever...

Descripción completa

Detalles Bibliográficos
Autores principales:	Casado-Fernández, Guiomar, Corona, Magdalena, Torres, Montserrat, Saez, Adolfo J., Ramos-Martín, Fernando, Manzanares, Mario, Vigón, Lorena, Mateos, Elena, Pozo, Francisco, Casas, Inmaculada, García-Gutierrez, Valentín, Rodríguez-Mora, Sara, Coiras, Mayte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915056/ https://www.ncbi.nlm.nih.gov/pubmed/36767310 http://dx.doi.org/10.3390/ijerph20031947

Ejemplares similares

Impaired Cytotoxic Response in PBMCs From Patients With COVID-19 Admitted to the ICU: Biomarkers to Predict Disease Severity
por: Vigón, Lorena, et al.
Publicado: (2021)

Impaired Antibody-Dependent Cellular Cytotoxicity in a Spanish Cohort of Patients With COVID-19 Admitted to the ICU
por: Vigón, Lorena, et al.
Publicado: (2021)

Early Cellular and Humoral Responses Developed in Oncohematological Patients after Vaccination with One Dose against COVID-19
por: Rodríguez-Mora, Sara, et al.
Publicado: (2022)

Persistent Overactive Cytotoxic Immune Response in a Spanish Cohort of Individuals With Long-COVID: Identification of Diagnostic Biomarkers
por: Galán, Miguel, et al.
Publicado: (2022)

Beneficial Effect of Short-Term Supplementation of High Dose of Vitamin D(3) in Hospitalized Patients With COVID-19: A Multicenter, Single-Blinded, Prospective Randomized Pilot Clinical Trial
por: Cervero, Miguel, et al.
Publicado: (2022)

Strong Cellular Immune Response, but Not Humoral, against SARS-CoV-2 in Oncohematological Patients with Autologous Stem Cell Transplantation after Natural Infection
por: Vigón, Lorena, et al.
Publicado: (2022)

Changes in the immune response against SARS-CoV-2 in individuals with severe COVID-19 treated with high dose of vitamin D
por: Torres, Montserrat, et al.
Publicado: (2022)

Regular Humoral and Cellular Immune Responses in Individuals with Chronic Myeloid Leukemia Who Received a Full Vaccination Schedule against COVID-19
por: Rodríguez-Mora, Sara, et al.
Publicado: (2023)

Characterization of the Humoral and Cellular Immune Response Against the Natural Infection By Sars-Cov-2 in Oncohematological Patients with Post-COVID19 Autologous Transplantation
por: Sánchez-Tornero, Adrián, et al.
Publicado: (2021)

PB1944: INDIVIDUALS WITH CHRONIC LYMPHOCYTIC LEUKAEMIA SHOW IMPAIRED HUMORAL BUT NORMAL CELLULAR IMMUNE RESPONSES AFTER RECEIVING A COMPLETE VACCINATION SCHEDULE AGAINST SARS-COV-2
por: Sánchez-Menéndez, Clara, et al.
Publicado: (2023)

Strong Humoral but Not Cellular Immune Responses against SARS-CoV-2 in Individuals with Oncohematological Disease Who Were Treated with Rituximab before Receiving a Vaccine Booster
por: Torres, Montserrat, et al.
Publicado: (2022)

Persistent Immunity against SARS-CoV-2 in Individuals with Oncohematological Diseases Who Underwent Autologous or Allogeneic Stem Cell Transplantation after Vaccination
por: Rodríguez-Mora, Sara, et al.
Publicado: (2023)

409. Unvaccinated Adolescents Bear the Majority of Disease Burden of Severe COVID-19 Among Those Admitted to the Intensive Care Unit (ICU)
por: Kaushik, Ashlesha, et al.
Publicado: (2023)

Association between HLA-C alleles and COVID-19 severity in a pilot study with a Spanish Mediterranean Caucasian cohort
por: Vigón, Lorena, et al.
Publicado: (2022)

Caring for Unvaccinated Patients in the ICU: Beyond Frustration, Toward Beneficial Relationships
por: Bibler, Trevor M., et al.
Publicado: (2021)

Characterization of the Early Humoral and Cellular Response Developed in Oncohematological Patients Post-Vaccination with One Dose Against COVID-19
por: Corona De Lapuerta, Magdalena, et al.
Publicado: (2021)

Caspase-3-mediated cleavage of p65/RelA results in a carboxy-terminal fragment that inhibits IκBα and enhances HIV-1 replication in human T lymphocytes
por: Coiras, Mayte, et al.
Publicado: (2008)

Unvaccinated COVID-19 patients in the ICU: Views from both sides of the barrier
por: Vianello, A., et al.
Publicado: (2022)

Identification of Immunological Parameters as Predictive Biomarkers of Relapse in Patients with Chronic Myeloid Leukemia on Treatment-Free Remission
por: Vigón, Lorena, et al.
Publicado: (2020)

Characteristics of COVID-19 vaccinated and unvaccinated patients admitted to Careggi University Hospital, Florence, Italy
por: Paggi, Riccardo, et al.
Publicado: (2023)

RWD34 Comparison of ICU/Ventilator Usage Among Vaccinated and Unvaccinated COVID-19 Patients
por: Roy, A, et al.
Publicado: (2022)

Sepsis in HIV patients admitted to the ICU
por: Vidal-Cortés, P, et al.
Publicado: (2013)

Healthcare-related bacteraemia admitted to the ICU
por: Castro, G, et al.
Publicado: (2008)

Caring for the Unvaccinated
por: Parker, William F.
Publicado: (2022)

Oral Care in Trauma Patients Admitted to the ICU: Viewpoints of ICU Nurses
por: Javadinia, Seyed Alireza, et al.
Publicado: (2014)

The mutation of Transportin 3 gene that causes limb girdle muscular dystrophy 1F induces protection against HIV-1 infection
por: Rodríguez-Mora, Sara, et al.
Publicado: (2019)

Incidence of pressure ulcers due to prone position in patients admitted to the ICU for Covid-19
por: Pérez-Juan, E., et al.
Publicado: (2023)

Mortality predictors in acute pancreatitis admitted to the ICU
por: Vidal-Cortés, P, et al.
Publicado: (2012)

Candida Colonization Index in Patients Admitted to an ICU
por: Caggiano, Giuseppina, et al.
Publicado: (2011)

Prognoses indicators of HIV patients admitted to the ICU
por: Moya, B, et al.
Publicado: (2010)

Outcome of bariatric surgical patients admitted to the ICU
por: de Marco, FVC, et al.
Publicado: (2005)

Prognosis of patients with haematological malignancies admitted to the ICU
por: Geerse, DA, et al.
Publicado: (2008)

Prognostic factors of elderly patients admitted to an ICU
por: Stein, F, et al.
Publicado: (2008)

Outcomes of patients with hematologic malignancies admitted to the ICU
por: Duayer, I, et al.
Publicado: (2015)

Prognosis of cirrhotic patients admitted to the general ICU
por: Piton, Gaël, et al.
Publicado: (2016)

A Study of Hypomagnesemia in Patients Admitted to the ICU
por: Santosh Raju, Kakarlapudi, et al.
Publicado: (2023)

Shoulder pain as residual injury after hospital discharge in patients admitted to ICU for COVID-19 pneumonia()
por: Puentes Gutiérrez, Ana Belén, et al.
Publicado: (2021)

PB2159: CHARACTERIZATION OF THE IMMUNE RESPONSE DEVELOPED IN PATIENTS WITH MULTIPLE MYELOMA AFTER RECEIVING TWO DOSES OF THE VACCINE AGAINST SARS-COV-2
por: Perez, Laura, et al.
Publicado: (2023)

Molecular mechanisms involved in HIV latency and implications for HIV treatment and eradication
por: Alcami, Jose, et al.
Publicado: (2010)

Managing Unvaccinated Staff
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ma4kcnq01tnrg6llicofnpheps