Mutations in Complex I of the Mitochondrial Electron-Transport Chain Sensitize the Fruit Fly (Drosophila melanogaster) to Ether and Non-Ether Volatile Anesthetics

The mitochondrial electron transport chain (mETC) contains molecular targets of volatile general anesthetics (VGAs), which places carriers of mutations at risk for anesthetic complications. The ND-23(60114) and mt:ND2(del1) lines of fruit flies (Drosophila melanogaster) that carry mutations in core...

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Detalles Bibliográficos
Autores principales: Borchardt, Luke A., Scharenbrock, Amanda R., Olufs, Zachariah P. G., Wassarman, David A., Perouansky, Misha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915120/
https://www.ncbi.nlm.nih.gov/pubmed/36768163
http://dx.doi.org/10.3390/ijms24031843

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