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The Nebulous Association between Cognitive Impairment and Falls in Older Adults: A Systematic Review of the Literature

Background: In older people, dementia is a well-established risk factor for falls. However, the association and the causal relationship between falls and the earlier stages of cognitive impairment remains unclear. The purpose of the study was to review the literature data on the association between...

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Autores principales: Leroy, Victoire, Martinet, Valérie, Nunkessore, Oumashankar, Dentel, Christel, Durand, Hélène, Mockler, David, Puisieux, François, Fougère, Bertrand, Chen, Yaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915123/
https://www.ncbi.nlm.nih.gov/pubmed/36767992
http://dx.doi.org/10.3390/ijerph20032628
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author Leroy, Victoire
Martinet, Valérie
Nunkessore, Oumashankar
Dentel, Christel
Durand, Hélène
Mockler, David
Puisieux, François
Fougère, Bertrand
Chen, Yaohua
author_facet Leroy, Victoire
Martinet, Valérie
Nunkessore, Oumashankar
Dentel, Christel
Durand, Hélène
Mockler, David
Puisieux, François
Fougère, Bertrand
Chen, Yaohua
author_sort Leroy, Victoire
collection PubMed
description Background: In older people, dementia is a well-established risk factor for falls. However, the association and the causal relationship between falls and the earlier stages of cognitive impairment remains unclear. The purpose of the study was to review the literature data on the association between falls and cognitive impairment, no dementia, including Mild Cognitive Impairment. Methods: According to PRISMA guidelines, we searched five electronic databases (EMBASE, Web of Science, Medline, CINAHL, and PsychINFO) for articles published between January 2011 and August 2022 on observational studies of older people with a cognitive assessment and/or cognitive impairment diagnosis and a recording of falls. Their quality was reviewed according to the STROBE checklist. Results: We selected 42 of the 4934 initially retrieved publications. In 24 retrospective studies, a statistically significant association between falls and cognitive status was found in only 15 of the 32 comparisons (47%). Of the 27 cross-sectional analyses in prospective studies, only eight (30%) were positive and significant. We counted four longitudinal analyses, half of which suggested a causal relationship between falls and cognitive impairment. The investigational methods varied markedly from one study to another. Conclusion: It is still not clear whether falls are associated with cognitive impairment, no dementia. Data in favor of a causal relationship are scarce. Further studies are needed to clarify their relationship.
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spelling pubmed-99151232023-02-11 The Nebulous Association between Cognitive Impairment and Falls in Older Adults: A Systematic Review of the Literature Leroy, Victoire Martinet, Valérie Nunkessore, Oumashankar Dentel, Christel Durand, Hélène Mockler, David Puisieux, François Fougère, Bertrand Chen, Yaohua Int J Environ Res Public Health Systematic Review Background: In older people, dementia is a well-established risk factor for falls. However, the association and the causal relationship between falls and the earlier stages of cognitive impairment remains unclear. The purpose of the study was to review the literature data on the association between falls and cognitive impairment, no dementia, including Mild Cognitive Impairment. Methods: According to PRISMA guidelines, we searched five electronic databases (EMBASE, Web of Science, Medline, CINAHL, and PsychINFO) for articles published between January 2011 and August 2022 on observational studies of older people with a cognitive assessment and/or cognitive impairment diagnosis and a recording of falls. Their quality was reviewed according to the STROBE checklist. Results: We selected 42 of the 4934 initially retrieved publications. In 24 retrospective studies, a statistically significant association between falls and cognitive status was found in only 15 of the 32 comparisons (47%). Of the 27 cross-sectional analyses in prospective studies, only eight (30%) were positive and significant. We counted four longitudinal analyses, half of which suggested a causal relationship between falls and cognitive impairment. The investigational methods varied markedly from one study to another. Conclusion: It is still not clear whether falls are associated with cognitive impairment, no dementia. Data in favor of a causal relationship are scarce. Further studies are needed to clarify their relationship. MDPI 2023-02-01 /pmc/articles/PMC9915123/ /pubmed/36767992 http://dx.doi.org/10.3390/ijerph20032628 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Systematic Review
Leroy, Victoire
Martinet, Valérie
Nunkessore, Oumashankar
Dentel, Christel
Durand, Hélène
Mockler, David
Puisieux, François
Fougère, Bertrand
Chen, Yaohua
The Nebulous Association between Cognitive Impairment and Falls in Older Adults: A Systematic Review of the Literature
title The Nebulous Association between Cognitive Impairment and Falls in Older Adults: A Systematic Review of the Literature
title_full The Nebulous Association between Cognitive Impairment and Falls in Older Adults: A Systematic Review of the Literature
title_fullStr The Nebulous Association between Cognitive Impairment and Falls in Older Adults: A Systematic Review of the Literature
title_full_unstemmed The Nebulous Association between Cognitive Impairment and Falls in Older Adults: A Systematic Review of the Literature
title_short The Nebulous Association between Cognitive Impairment and Falls in Older Adults: A Systematic Review of the Literature
title_sort nebulous association between cognitive impairment and falls in older adults: a systematic review of the literature
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915123/
https://www.ncbi.nlm.nih.gov/pubmed/36767992
http://dx.doi.org/10.3390/ijerph20032628
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