Cargando…

ADHD Prevalence among Outpatients with Severe Opioid Use Disorder on Daily Intravenous Diamorphine and/or Oral Opioid Maintenance Treatment

(1) Background: Attention deficit hyperactivity disorder (ADHD) is a common comorbid condition in opioid use disorder (OUD) and is associated with a more severe course of substance use. Patients with severe OUD who have not responded to oral opioid maintenance treatment can be treated with intraveno...

Descripción completa

Detalles Bibliográficos
Autores principales: Rohner, Henrik, Gaspar, Nikolas, Rosen, Helena, Ebert, Tim, Kilarski, Laura Luisa, Schrader, Felix, Al Istwani, Moaz, Lenz, Anna Julia, Dilg, Christoph, Welskop, Andrea, Goldmann, Tatjana, Schmidt, Ulrike, Philipsen, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915278/
https://www.ncbi.nlm.nih.gov/pubmed/36767906
http://dx.doi.org/10.3390/ijerph20032534
_version_ 1784885865682567168
author Rohner, Henrik
Gaspar, Nikolas
Rosen, Helena
Ebert, Tim
Kilarski, Laura Luisa
Schrader, Felix
Al Istwani, Moaz
Lenz, Anna Julia
Dilg, Christoph
Welskop, Andrea
Goldmann, Tatjana
Schmidt, Ulrike
Philipsen, Alexandra
author_facet Rohner, Henrik
Gaspar, Nikolas
Rosen, Helena
Ebert, Tim
Kilarski, Laura Luisa
Schrader, Felix
Al Istwani, Moaz
Lenz, Anna Julia
Dilg, Christoph
Welskop, Andrea
Goldmann, Tatjana
Schmidt, Ulrike
Philipsen, Alexandra
author_sort Rohner, Henrik
collection PubMed
description (1) Background: Attention deficit hyperactivity disorder (ADHD) is a common comorbid condition in opioid use disorder (OUD) and is associated with a more severe course of substance use. Patients with severe OUD who have not responded to oral opioid maintenance treatment can be treated with intravenous diamorphine up to three times per day. Here, we investigated the prevalence of ADHD among patients undergoing either daily diamorphine maintenance treatment or daily oral opioid maintenance treatment. (2) Methods: We assessed all participants with the WURS-k and the ADHD-SR. The Diagnostic Interview for ADHD in Adults (DIVA) was performed with all participants who met the cut-off in the WURS-k and/or ADHD-SR. (3) Results: The overall prevalence of ADHD was 17.9%. Prevalence of ADHD among patients undergoing daily diamorphine maintenance treatment was 14.3%. Prevalence of ADHD among patients undergoing daily oral opioid maintenance treatment was 20.3%. The combined presentation of ADHD was the most prevalent condition. In urine samples of participants with comorbid ADHD, heroin was detected the most and cocaine the least frequently. (4) Conclusions: Almost one out of five patients with OUD suffered from comorbid ADHD. In 83.3%, ADHD had not been diagnosed prior to participation in this study. Thus, patients with SUD could benefit from being routinely screened for ADHD.
format Online
Article
Text
id pubmed-9915278
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-99152782023-02-11 ADHD Prevalence among Outpatients with Severe Opioid Use Disorder on Daily Intravenous Diamorphine and/or Oral Opioid Maintenance Treatment Rohner, Henrik Gaspar, Nikolas Rosen, Helena Ebert, Tim Kilarski, Laura Luisa Schrader, Felix Al Istwani, Moaz Lenz, Anna Julia Dilg, Christoph Welskop, Andrea Goldmann, Tatjana Schmidt, Ulrike Philipsen, Alexandra Int J Environ Res Public Health Article (1) Background: Attention deficit hyperactivity disorder (ADHD) is a common comorbid condition in opioid use disorder (OUD) and is associated with a more severe course of substance use. Patients with severe OUD who have not responded to oral opioid maintenance treatment can be treated with intravenous diamorphine up to three times per day. Here, we investigated the prevalence of ADHD among patients undergoing either daily diamorphine maintenance treatment or daily oral opioid maintenance treatment. (2) Methods: We assessed all participants with the WURS-k and the ADHD-SR. The Diagnostic Interview for ADHD in Adults (DIVA) was performed with all participants who met the cut-off in the WURS-k and/or ADHD-SR. (3) Results: The overall prevalence of ADHD was 17.9%. Prevalence of ADHD among patients undergoing daily diamorphine maintenance treatment was 14.3%. Prevalence of ADHD among patients undergoing daily oral opioid maintenance treatment was 20.3%. The combined presentation of ADHD was the most prevalent condition. In urine samples of participants with comorbid ADHD, heroin was detected the most and cocaine the least frequently. (4) Conclusions: Almost one out of five patients with OUD suffered from comorbid ADHD. In 83.3%, ADHD had not been diagnosed prior to participation in this study. Thus, patients with SUD could benefit from being routinely screened for ADHD. MDPI 2023-01-31 /pmc/articles/PMC9915278/ /pubmed/36767906 http://dx.doi.org/10.3390/ijerph20032534 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Rohner, Henrik
Gaspar, Nikolas
Rosen, Helena
Ebert, Tim
Kilarski, Laura Luisa
Schrader, Felix
Al Istwani, Moaz
Lenz, Anna Julia
Dilg, Christoph
Welskop, Andrea
Goldmann, Tatjana
Schmidt, Ulrike
Philipsen, Alexandra
ADHD Prevalence among Outpatients with Severe Opioid Use Disorder on Daily Intravenous Diamorphine and/or Oral Opioid Maintenance Treatment
title ADHD Prevalence among Outpatients with Severe Opioid Use Disorder on Daily Intravenous Diamorphine and/or Oral Opioid Maintenance Treatment
title_full ADHD Prevalence among Outpatients with Severe Opioid Use Disorder on Daily Intravenous Diamorphine and/or Oral Opioid Maintenance Treatment
title_fullStr ADHD Prevalence among Outpatients with Severe Opioid Use Disorder on Daily Intravenous Diamorphine and/or Oral Opioid Maintenance Treatment
title_full_unstemmed ADHD Prevalence among Outpatients with Severe Opioid Use Disorder on Daily Intravenous Diamorphine and/or Oral Opioid Maintenance Treatment
title_short ADHD Prevalence among Outpatients with Severe Opioid Use Disorder on Daily Intravenous Diamorphine and/or Oral Opioid Maintenance Treatment
title_sort adhd prevalence among outpatients with severe opioid use disorder on daily intravenous diamorphine and/or oral opioid maintenance treatment
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915278/
https://www.ncbi.nlm.nih.gov/pubmed/36767906
http://dx.doi.org/10.3390/ijerph20032534
work_keys_str_mv AT rohnerhenrik adhdprevalenceamongoutpatientswithsevereopioidusedisorderondailyintravenousdiamorphineandororalopioidmaintenancetreatment
AT gasparnikolas adhdprevalenceamongoutpatientswithsevereopioidusedisorderondailyintravenousdiamorphineandororalopioidmaintenancetreatment
AT rosenhelena adhdprevalenceamongoutpatientswithsevereopioidusedisorderondailyintravenousdiamorphineandororalopioidmaintenancetreatment
AT eberttim adhdprevalenceamongoutpatientswithsevereopioidusedisorderondailyintravenousdiamorphineandororalopioidmaintenancetreatment
AT kilarskilauraluisa adhdprevalenceamongoutpatientswithsevereopioidusedisorderondailyintravenousdiamorphineandororalopioidmaintenancetreatment
AT schraderfelix adhdprevalenceamongoutpatientswithsevereopioidusedisorderondailyintravenousdiamorphineandororalopioidmaintenancetreatment
AT alistwanimoaz adhdprevalenceamongoutpatientswithsevereopioidusedisorderondailyintravenousdiamorphineandororalopioidmaintenancetreatment
AT lenzannajulia adhdprevalenceamongoutpatientswithsevereopioidusedisorderondailyintravenousdiamorphineandororalopioidmaintenancetreatment
AT dilgchristoph adhdprevalenceamongoutpatientswithsevereopioidusedisorderondailyintravenousdiamorphineandororalopioidmaintenancetreatment
AT welskopandrea adhdprevalenceamongoutpatientswithsevereopioidusedisorderondailyintravenousdiamorphineandororalopioidmaintenancetreatment
AT goldmanntatjana adhdprevalenceamongoutpatientswithsevereopioidusedisorderondailyintravenousdiamorphineandororalopioidmaintenancetreatment
AT schmidtulrike adhdprevalenceamongoutpatientswithsevereopioidusedisorderondailyintravenousdiamorphineandororalopioidmaintenancetreatment
AT philipsenalexandra adhdprevalenceamongoutpatientswithsevereopioidusedisorderondailyintravenousdiamorphineandororalopioidmaintenancetreatment