Single-cell RNA sequencing reveals dysregulated fibroblast subclusters in prurigo nodularis

Prurigo nodularis (PN) is an intensely pruritic, chronic inflammatory skin disease that disproportionately affects black patients. However, the pathogenesis of PN is poorly understood. We performed single-cell transcriptomic profiling, ligand receptor analysis and cell trajectory analysis of 28,695...

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Detalles Bibliográficos
Autores principales: Patel, Jay R., Joel, Marina Z., Lee, Kevin K., Kambala, Anusha, Cornman, Hannah, Oladipo, Olusola, Taylor, Matthew, Deng, June, Parthasarathy, Varsha, Cravero, Karen, Marani, Melika, Zhao, Ryan, Sankararam, Sreenidhi, Li, Ruixiang, Pritchard, Thomas, Rebecca, Vito, Kwatra, Madan M., Ho, Won Jin, Dong, Xinzhong, Kang, Sewon, Kwatra, Shawn G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915465/
https://www.ncbi.nlm.nih.gov/pubmed/36778229
http://dx.doi.org/10.1101/2023.01.29.526050

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