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Selective deletion of Methyl CpG binding protein 2 from parvalbumin interneurons in the auditory cortex delays the onset of maternal retrieval in mice

Mutations in MECP2 cause the neurodevelopmental disorder Rett syndrome. MECP2 codes for methyl CpG binding protein 2 (MECP2), a transcriptional regulator that activates genetic programs for experience-dependent plasticity. Many neural and behavioral symptoms of Rett syndrome may result from dysregul...

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Detalles Bibliográficos
Autores principales: Rupert, Deborah D., Pagliaro, Alexa, Choe, Jane, Shea, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915474/
https://www.ncbi.nlm.nih.gov/pubmed/36778467
http://dx.doi.org/10.1101/2023.01.30.526321