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Analysis of nucleotide variations in human g-quadruplex forming regions associated with disease states
While the role of G4 G quadruplex structures has been identified in cancers and metabolic disorders, single nucleotide variations (SNVs) and their effect on G4s in disease contexts have not been extensively studied. The COSMIC and CLINVAR databases were used to detect SNVs present in G4s to identify...
Autores principales: | Neupane, Aryan, Chariker, Julia H., Rouchka, Eric C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915501/ https://www.ncbi.nlm.nih.gov/pubmed/36778288 http://dx.doi.org/10.1101/2023.01.30.526341 |
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