Cargando…

Hypermetabolism in mice carrying a near complete human chromosome 21

The consequences of aneuploidy have traditionally been studied in cell and animal models in which the extrachromosomal DNA is from the same species. Here, we explore a fundamental question concerning the impact of aneuploidy on systemic metabolism using a non-mosaic transchromosomic mouse model (TcM...

Descripción completa

Detalles Bibliográficos
Autores principales: Sarver, Dylan C., Xu, Cheng, Rodriguez, Susana, Aja, Susan, Jaffe, Andrew E., Gao, Feng J., Delannoy, Michael, Periasamy, Muthu, Kazuki, Yasuhiro, Oshimura, Mitsuo, Reeves, Roger H., Wong, G. William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915508/
https://www.ncbi.nlm.nih.gov/pubmed/36778465
http://dx.doi.org/10.1101/2023.01.30.526183

Ejemplares similares