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Fitness effects of mutations to SARS-CoV-2 proteins
Knowledge of the fitness effects of mutations to SARS-CoV-2 can inform assessment of new variants, design of therapeutics resistant to escape, and understanding of the functions of viral proteins. However, experimentally measuring effects of mutations is challenging: we lack tractable lab assays for...
Autores principales: | Bloom, Jesse D., Neher, Richard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915511/ https://www.ncbi.nlm.nih.gov/pubmed/36778462 http://dx.doi.org/10.1101/2023.01.30.526314 |
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