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Multi-input drug-controlled switches of mammalian gene expression based on engineered nuclear hormone receptors
Protein-based switches that respond to different inputs to regulate cellular outputs, such as gene expression, are central to synthetic biology. For increased controllability, multi-input switches that integrate several cooperating and competing signals for the regulation of a shared output are of p...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915577/ https://www.ncbi.nlm.nih.gov/pubmed/36778233 http://dx.doi.org/10.1101/2023.02.01.526549 |