Human cytomegalovirus mediates APOBEC3B relocalization early during infection through a ribonucleotide reductase-independent mechanism

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The APOBEC3 family of DNA cytosine deaminases comprises an important arm of the innate antiviral defense system. The gamma-herpesviruses EBV and KSHV and the alpha-herpesviruses HSV-1 and HSV-2 have evolved an efficient mechanism to avoid APOBEC3 restriction by directly binding to APOBEC3B and facil...

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Detalles Bibliográficos
Autores principales: Fanunza, Elisa, Cheng, Adam Z., Auerbach, Ashley A., Stefanovska, Bojana, Moraes, Sofia N., Lokensgard, James R., Biolatti, Matteo, Dell’Oste, Valentina, Bierle, Craig J., Bresnahan, Wade A., Harris, Reuben S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915650/
https://www.ncbi.nlm.nih.gov/pubmed/36778493
http://dx.doi.org/10.1101/2023.01.30.526383
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