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Experiment-based Computational Model Predicts that IL-6 Trans-Signaling Plays a Dominant Role in IL-6 mediated signaling in Endothelial Cells

Inflammatory cytokine mediated responses are important in the development of many diseases that are associated with angiogenesis. Targeting angiogenesis as a prominent strategy has shown limited effects in many contexts such as peripheral arterial disease (PAD) and cancer. One potential reason for t...

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Detalles Bibliográficos
Autores principales: Song, Min, Wang, Youli, Annex, Brian H., Popel, Aleksander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915676/
https://www.ncbi.nlm.nih.gov/pubmed/36778489
http://dx.doi.org/10.1101/2023.02.03.526721

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