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An unbiased, automated platform for scoring dopaminergic neurodegeneration in C. elegans
Caenorhabditis elegans (C. elegans) has served as a simple model organism to study dopaminergic neurodegeneration, as it enables quantitative analysis of cellular and sub-cellular morphologies in live animals. These isogenic nematodes have a rapid life cycle and transparent body, making high-through...
Autores principales: | Clark, Andrew S., Kalmanson, Zachary, Morton, Katherine, Hartman, Jessica, Meyer, Joel, San-Miguel, Adriana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915681/ https://www.ncbi.nlm.nih.gov/pubmed/36778421 http://dx.doi.org/10.1101/2023.02.02.526781 |
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