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An unbiased, automated platform for scoring dopaminergic neurodegeneration in C. elegans

Caenorhabditis elegans (C. elegans) has served as a simple model organism to study dopaminergic neurodegeneration, as it enables quantitative analysis of cellular and sub-cellular morphologies in live animals. These isogenic nematodes have a rapid life cycle and transparent body, making high-through...

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Detalles Bibliográficos
Autores principales: Clark, Andrew S., Kalmanson, Zachary, Morton, Katherine, Hartman, Jessica, Meyer, Joel, San-Miguel, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915681/
https://www.ncbi.nlm.nih.gov/pubmed/36778421
http://dx.doi.org/10.1101/2023.02.02.526781