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Polypharmacology-based kinome screen identifies new regulators of KSHV reactivation

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Kaposi’s sarcoma-associated herpesvirus (KSHV) causes several human diseases including Kaposi’s sarcoma (KS), a leading cause of cancer in Africa and in patients with AIDS. KS tumor cells harbor KSHV predominantly in a latent form, while typically <5% contain lytic replicating virus. Because both...

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Detalles Bibliográficos
Autores principales:	Olson, Annabel T., Kang, Yuqi, Ladha, Anushka M., Lim, Chuan Bian, Lagunoff, Michael, Gujral, Taran S., Geballe, Adam P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915688/ https://www.ncbi.nlm.nih.gov/pubmed/36778430 http://dx.doi.org/10.1101/2023.02.01.526589

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