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Tubular Mitochondrial Pyruvate Carrier Disruption Elicits Redox Adaptations that Protect from Acute Kidney Injury
Energy-intensive kidney reabsorption processes essential for normal whole-body function are maintained by tubular epithelial cell metabolism. Tubular metabolism changes markedly following acute kidney injury (AKI), but which changes are adaptive versus maladaptive remain poorly understood. In public...
Autores principales: | Rauckhorst, Adam J., Martinez, Gabriela Vasquez, Andrade, Gabriel Mayoral, Wen, Hsiang, Kim, Ji Young, Simoni, Aaron, Mapuskar, Kranti A., Rastogi, Prerna, Steinbach, Emily J, McCormick, Michael L., Allen, Bryan G., Pabla, Navjot S., Jackson, Ashley R., Coleman, Mitchell C., Spitz, Douglas R., Taylor, Eric B., Zepeda-Orozco, Diana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915694/ https://www.ncbi.nlm.nih.gov/pubmed/36778297 http://dx.doi.org/10.1101/2023.01.31.526492 |
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