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A novel binding site on the cryptic intervening domain is a motif-dependent regulator of O-GlcNAc transferase
The modification of intracellular proteins with O-linked β-N-acetylglucosamme (O-GlcNAc) moieties is a highly dynamic process that spatiotemporally regulates nearly every important cellular program. Despite its significance, little is known about the substrate recognition and regulation modes of O-G...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915769/ https://www.ncbi.nlm.nih.gov/pubmed/36778302 http://dx.doi.org/10.21203/rs.3.rs-2531412/v1 |