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A novel binding site on the cryptic intervening domain is a motif-dependent regulator of O-GlcNAc transferase

The modification of intracellular proteins with O-linked β-N-acetylglucosamme (O-GlcNAc) moieties is a highly dynamic process that spatiotemporally regulates nearly every important cellular program. Despite its significance, little is known about the substrate recognition and regulation modes of O-G...

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Detalles Bibliográficos
Autores principales: Blankenship, Connor, Xie, Jinshan, Benz, Caroline, Wang, Ao, Ivarsson, Ylva, Jiang, Jiaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915769/
https://www.ncbi.nlm.nih.gov/pubmed/36778302
http://dx.doi.org/10.21203/rs.3.rs-2531412/v1