Cargando…
Unstable EBV latency drives inflammation in multiple sclerosis patient derived spontaneous B cells
Epidemiological studies have demonstrated that Epstein-Barr virus (EBV) is a known etiologic risk factor, and perhaps prerequisite, for the development of MS. EBV establishes life-long latent infection in a subpopulation of memory B cells. Although the role of memory B cells in the pathobiology of M...
Autores principales: | Soldan, Samantha, Su, Chenhe, Monaco, Maria Chiara, Brown, Natalie, Clauze, Annaliese, Andrada, Frances, Feder, Andries, Planet, Paul, Kossenkov, Andrew, Schäffer, Daniel, Ohayon, Joan, Auslander, Noam, Jacobson, Steve, Lieberman, Paul |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915775/ https://www.ncbi.nlm.nih.gov/pubmed/36778367 http://dx.doi.org/10.21203/rs.3.rs-2398872/v1 |
Ejemplares similares
-
EBNA1 Inhibitors Block Proliferation of Spontaneous Lymphoblastoid Cell Lines From Patients With Multiple Sclerosis and Healthy Controls
por: Monaco, Maria Chiara G., et al.
Publicado: (2023) -
EBV Latency Types Adopt Alternative Chromatin Conformations
por: Tempera, Italo, et al.
Publicado: (2011) -
EBNA2 driven enhancer switching at the CIITA-DEXI locus suppresses HLA class II gene expression during EBV infection of B-lymphocytes
por: Su, Chenhe, et al.
Publicado: (2021) -
CTCF Prevents the Epigenetic Drift of EBV Latency Promoter Qp
por: Tempera, Italo, et al.
Publicado: (2010) -
Decitabine disrupts EBV genomic epiallele DNA methylation patterns around CTCF binding sites to increase chromatin accessibility and lytic transcription in gastric cancer
por: Preston-Alp, Sarah, et al.
Publicado: (2023)