Astrocyte reactivity influences the association of amyloid-β and tau biomarkers in preclinical Alzheimer’s disease

An unresolved question for the understanding of Alzheimer’s disease (AD) pathophysiology is why a significant percentage of amyloid β (Aβ)-positive cognitively unimpaired (CU) individuals do not develop detectable downstream tau pathology and, consequently, clinical deterioration. In vitro evidence...

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Detalles Bibliográficos
Autores principales: Pascoal, Tharick, Bellaver, Bruna, Povala, Guilherme, Ferreira, Pamela, Ferrari-Souza, João Pedro, Leffa, Douglas, Lussier, Firoza, Benedet, Andrea, Ashton, Nicholas, Triana-Baltzerz, Gallen, Kolbzh, Hartmuth, Tissot, Cèile, Therriault, Joseph, Servaes, Stijn, Stevenson, Jenna, Rahmouni, Nesrine, Lopez, Oscar, Tudorascu, Dana, Villemagne, Victor, Ikonomovic, Milos, Gauthier, Serge, Zimmer, Eduardo, Zetterberg, Henrik, Blennow, Kaj, Aizenstein, Howard, Klunk, William, Snitz, Beth, Maki, Pauline, Thurston, Rebecca, Cohen, Ann, Ganguli, Mary, Karikari, Thomas, Rosa-Neto, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915798/
https://www.ncbi.nlm.nih.gov/pubmed/36778243
http://dx.doi.org/10.21203/rs.3.rs-2507179/v1

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