Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies

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TAR DNA-binding protein-43 (TDP-43) accumulation is the primary pathology underlying several neurodegenerative diseases. Charting the progression and heterogeneity of TDP-43 accumulation is necessary to better characterise TDP-43 proteinopathies, but current TDP-43 staging systems are heuristic and...

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Detalles Bibliográficos
Autores principales: Young, Alexandra L, Vogel, Jacob W, Robinson, John L, McMillan, Corey T, Ossenkoppele, Rik, Wolk, David A., Irwin, David J., Elman, Lauren, Grossman, Murray, Lee, Virginia M-Y, Lee, Edward B, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915837/
https://www.ncbi.nlm.nih.gov/pubmed/36778217
http://dx.doi.org/10.1101/2023.01.31.23285242
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