Increased Levels of the Parkinson’s Disease-Associated Gene ITPKB Correlate with Higher Expression Levels of α-Synuclein, Independent of Mutation Status

Autosomal dominant mutations in the gene encoding α-synuclein (SNCA) were the first to be linked with hereditary Parkinson’s disease (PD). Duplication and triplication of SNCA has been observed in PD patients, together with mutations at the N-terminal of the protein, among which A30P and A53T influe...

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Detalles Bibliográficos
Autores principales: Di Leva, Francesca, Filosi, Michele, Oyston, Lisa, Silvestri, Erica, Picard, Anne, Lavdas, Alexandros A., Lobbestael, Evy, Baekelandt, Veerle, Neely, G. Gregory, Pramstaller, Peter P., Hicks, Andrew A., Corti, Corrado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916293/
https://www.ncbi.nlm.nih.gov/pubmed/36768321
http://dx.doi.org/10.3390/ijms24031984

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