Cargando…

Deep Molecular Response Achieved with Chemotherapy, Dasatinib and Interferon α in Patients with Lymphoid Blast Crisis of Chronic Myeloid Leukaemia

The treatment outcome in patients with chronic myeloid leukaemia (CML) in blast crisis (BC) is unsatisfactory despite the use of allogeneic stem cell transplantation (ASCT). Moreover, in some patients ASCT is contraindicated, with limited treatment options. We report the case series of two patients...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vráblová, Lucia, Divoký, Vladimír, Kořalková, Pavla, Poláková, Kateřina Machová, Kriegová, Eva, Janská, Romana, Grohmann, Jan, Holzerová, Milena, Papajík, Tomáš, Faber, Edgar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916434/ https://www.ncbi.nlm.nih.gov/pubmed/36768374 http://dx.doi.org/10.3390/ijms24032050

Ejemplares similares

PB1883: IMPLANTATION AND LONG-TERM USE OF PERIPHERALLY-INSERTED CENTRAL CATHETER ARE SAFE IN PATIENTS WITH ACUTE PROMYELOCYTIC LEUKAEMIA
por: Szotkowski, Tomáš, et al.
Publicado: (2023)

S152: COMBINATORY THERAPY OF ASCIMINIB AND PONATINIB WAS EFFECTIVE IN THE TREATMENT OF BLAST PHASE CML CDX MODEL
por: Čuřík, Nikola, et al.
Publicado: (2023)

Isolated central nervous system blast crisis in a case of chronic myeloid leukemia on dasatinib
por: Kiran, P. K., et al.
Publicado: (2018)

Molecular evidence for the clonal origin of blast crisis in chronic myeloid leukaemia.
por: Zalcberg, J. R., et al.
Publicado: (1986)

The Lymphoid Leukaemias
por: Stevenson, G. T.
Publicado: (1991)

Oxidative DNA Damage, Inflammatory Signature, and Altered Erythrocytes Properties in Diamond-Blackfan Anemia
por: Kapralova, Katarina, et al.
Publicado: (2020)

Pediatric chronic myeloid leukemia with B-cell lymphoid blast crisis at presentation
por: Iyer, Prasad, et al.
Publicado: (2013)

Bilateral Serous Retinal Detachment in Lymphoid Blast Crisis of Chronic Myeloid Leukemia
por: Umemura, Kyohei, et al.
Publicado: (2021)

Dasatinib as the salvage therapy for chronic myeloid leukemia with blast crisis and central nervous system involvement: A case report
por: LAI, SHIUE-WEI, et al.
Publicado: (2015)

Dasatinib and FLAG-IDA Is an Effective Therapy for Initial Myeloid Blast Crisis but Involves a High Risk of Opportunistic Infections
por: Labrador, Jorge, et al.
Publicado: (2020)

Towards a Better Characterisation of Leukemic Cells in Chronic Lymphocytic Leukaemia: Cell-Size Heterogeneity Reflects Their Activation Status and Migratory Abilities
por: Manukyan, Gayane, et al.
Publicado: (2021)

Structural Insights into the Activation of the RhoA GTPase by the Lymphoid Blast Crisis (Lbc) Oncoprotein
por: Lenoir, Marc, et al.
Publicado: (2014)

Lymphoid blast crisis after prolonged treatment‐free remission in chronic myeloid leukaemia after tyrosine kinase inhibitor de‐escalation during the COVID‐19 pandemic
por: Avenoso, Daniele, et al.
Publicado: (2021)

Efficacy of Dasatinib in a CML Patient in Blast Crisis with F317L Mutation: A Case Report and Literature Review
por: Morozova, E.V., et al.
Publicado: (2015)

A case of chronic myeloid leukaemia presenting as megakaryocytic blast crisis (AML M7)
por: Karkuzhali, Ponnuswamy, et al.
Publicado: (2013)

Blast Crisis
por: Kirwin, Margaret, et al.
Publicado: (2020)

Role of DNA Damage Response in Suppressing Malignant Progression of Chronic Myeloid Leukemia and Polycythemia Vera: Impact of Different Oncogenes
por: Stetka, Jan, et al.
Publicado: (2020)

Spinal Chloroma – Herald of blast crisis in a patient with chronic myeloid leukaemia: A case report
por: Chandola, Stuti, et al.
Publicado: (2022)

Successful treatment of T315I BCR-ABL mutated lymphoid blast phase chronic myeloid leukemia with chimeric antigen receptor T cell therapy followed by dasatinib
por: Zhang, Hao, et al.
Publicado: (2020)

Role of Epigenetics in Chronic Myeloid Leukemia
por: Machova Polakova, Katerina, et al.
Publicado: (2013)

Primary del 17 chronic lymphocytic leukaemia lymphocytes are hypersensitive to dasatinib in vitro
por: Amrein, Lilian, et al.
Publicado: (2009)

Imatinib failure and response to dasatinib in a patient with chronic myeloid leukemia in blast crisis and a novel, nine-nucleotide BCR-ABL insertion mutation
por: Sigl, M, et al.
Publicado: (2013)

Seasonality in the presentation of acute lymphoid leukaemia.
por: Gilman, E. A., et al.
Publicado: (1998)

Real-Time Analysis of Imatinib- and Dasatinib-Induced Effects on Chronic Myelogenous Leukemia Cell Interaction with Fibronectin
por: Obr, Adam, et al.
Publicado: (2014)

ReSETting PP2A tumour suppressor activity in blast crisis and imatinib-resistant chronic myelogenous leukaemia
por: Perrotti, D, et al.
Publicado: (2006)

Chronic myeloid leukemia with an e1a3 BCR-ABL fusion protein: transformation to lymphoid blast crisis
por: Martinez-Serra, Jordi, et al.
Publicado: (2014)

Metabolic plasticity in blast crisis-chronic myeloid leukaemia cells under hypoxia reduces the cytotoxic potency of drugs targeting mitochondria
por: Salaverry, Luciana S., et al.
Publicado: (2022)

Alterations of Gab2 signalling complexes in imatinib and dasatinib treated chronic myeloid leukaemia cells
por: Halbach, Sebastian, et al.
Publicado: (2013)

Adverse effects of dasatinib on glucose-lipid metabolism in patients with chronic myeloid leukaemia in the chronic phase
por: Yu, Lu, et al.
Publicado: (2019)

Resistance-Associated Mutations in Chronic Lymphocytic Leukemia Patients Treated With Novel Agents
por: Sedlarikova, Lenka, et al.
Publicado: (2020)

AFLP-AFLP in silico-NGS approach reveals polymorphisms in repetitive elements in the malignant genome
por: Koblihova, Jitka, et al.
Publicado: (2018)

Monocytic myeloid‐derived suppressor cells as prognostic factor in chronic myeloid leukaemia patients treated with dasatinib
por: Giallongo, Cesarina, et al.
Publicado: (2017)

Dasatinib‐induced chylothorax in a patient with chronic myeloid leukaemia: a case report and literature review
por: Hsu, Chao‐Chin, et al.
Publicado: (2021)

Deciphering the complex circulating immune cell microenvironment in chronic lymphocytic leukaemia using patient similarity networks
por: Mikulkova, Zuzana, et al.
Publicado: (2021)

Cellular sensitization in chronic myeloid leukaemia patients to leukaemic blast antigens.
por: Gangal, S. G., et al.
Publicado: (1979)

Planet of the AAVs: The Spinal Cord Injury Episode
por: Stepankova, Katerina, et al.
Publicado: (2021)

The specific PKC-α inhibitor chelerythrine blunts costunolide-induced eryptosis
por: Ghashghaeinia, Mehrdad, et al.
Publicado: (2020)

Dasatinib Inhibits CXCR4 Signaling in Chronic Lymphocytic Leukaemia Cells and Impairs Migration Towards CXCL12
por: McCaig, Alison M., et al.
Publicado: (2012)

Combination of arsenic trioxide and Dasatinib: a new strategy to treat Philadelphia chromosome‐positive acute lymphoblastic leukaemia
por: Wang, Tao, et al.
Publicado: (2017)

Activation of ERK1/2 by MOS and TPL2 leads to dasatinib resistance in chronic myeloid leukaemia cells
por: Tsubaki, Masanobu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_b06hnuj5jfutbivp5ah6l0775i