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Overcoming cancer-associated fibroblast-induced immunosuppression by anti-interleukin-6 receptor antibody
Cancer-associated fibroblasts (CAFs) are a critical component of the tumor microenvironment and play a central role in tumor progression. Previously, we reported that CAFs might induce tumor immunosuppression via interleukin-6 (IL-6) and promote tumor progression by blocking local IL-6 in the tumor...
Autores principales: | Nishiwaki, Noriyuki, Noma, Kazuhiro, Ohara, Toshiaki, Kunitomo, Tomoyoshi, Kawasaki, Kento, Akai, Masaaki, Kobayashi, Teruki, Narusaka, Toru, Kashima, Hajime, Sato, Hiroaki, Komoto, Satoshi, Kato, Takuya, Maeda, Naoaki, Kikuchi, Satoru, Tanabe, Shunsuke, Tazawa, Hiroshi, Shirakawa, Yasuhiro, Fujiwara, Toshiyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916502/ https://www.ncbi.nlm.nih.gov/pubmed/36764954 http://dx.doi.org/10.1007/s00262-023-03378-7 |
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