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Spotlight on CYP4B1
The mammalian cytochrome P450 monooxygenase CYP4B1 can bioactivate a wide range of xenobiotics, such as its defining/hallmark substrate 4-ipomeanol leading to tissue-specific toxicities. Similar to other members of the CYP4 family, CYP4B1 has the ability to hydroxylate fatty acids and fatty alcohols...
Autores principales: | Röder, Annika, Hüsken, Saskia, Hutter, Michael C., Rettie, Allan E., Hanenberg, Helmut, Wiek, Constanze, Girhard, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916508/ https://www.ncbi.nlm.nih.gov/pubmed/36768362 http://dx.doi.org/10.3390/ijms24032038 |
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