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Hydroxytyrosol Reduces Foam Cell Formation and Endothelial Inflammation Regulating the PPARγ/LXRα/ABCA1 Pathway

Cholesterol accumulation in macrophages leads to the formation of foam cells and increases the risk of developing atherosclerosis. We have verified whether hydroxytyrosol (HT), a phenolic compound with anti-inflammatory and antioxidant properties, can reduce the cholesterol build up in THP-1 macroph...

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Detalles Bibliográficos
Autores principales: Franceschelli, Sara, De Cecco, Federica, Pesce, Mirko, Ripari, Patrizio, Guagnano, Maria Teresa, Nuevo, Arturo Bravo, Grilli, Alfredo, Sancilio, Silvia, Speranza, Lorenza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916557/
https://www.ncbi.nlm.nih.gov/pubmed/36768382
http://dx.doi.org/10.3390/ijms24032057