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Hydroxytyrosol Reduces Foam Cell Formation and Endothelial Inflammation Regulating the PPARγ/LXRα/ABCA1 Pathway
Cholesterol accumulation in macrophages leads to the formation of foam cells and increases the risk of developing atherosclerosis. We have verified whether hydroxytyrosol (HT), a phenolic compound with anti-inflammatory and antioxidant properties, can reduce the cholesterol build up in THP-1 macroph...
Autores principales: | Franceschelli, Sara, De Cecco, Federica, Pesce, Mirko, Ripari, Patrizio, Guagnano, Maria Teresa, Nuevo, Arturo Bravo, Grilli, Alfredo, Sancilio, Silvia, Speranza, Lorenza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916557/ https://www.ncbi.nlm.nih.gov/pubmed/36768382 http://dx.doi.org/10.3390/ijms24032057 |
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