The Intertwined Role of 8-oxodG and G4 in Transcription Regulation

The guanine base in nucleic acids is, among the other bases, the most susceptible to being converted into 8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) when exposed to reactive oxygen species. In double-helix DNA, 8-oxodG can pair with adenine; hence, it may cause a G > T (C > A) mutation; it...

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Detalles Bibliográficos
Autores principales: Gorini, Francesca, Ambrosio, Susanna, Lania, Luigi, Majello, Barbara, Amente, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916577/
https://www.ncbi.nlm.nih.gov/pubmed/36768357
http://dx.doi.org/10.3390/ijms24032031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916577/
https://www.ncbi.nlm.nih.gov/pubmed/36768357
http://dx.doi.org/10.3390/ijms24032031

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