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Metformin regulates myoblast differentiation through an AMPK-dependent mechanism

This study aims to investigate how metformin (Met) affects muscle tissue by evaluating the drug effects on proliferating, differentiating, and differentiated C2C12 cells. Moreover, we also investigated the role of 5’-adenosine monophosphate-activated protein kinase (AMPK) in the mechanism of action...

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Detalles Bibliográficos
Autores principales:	Maniscalco, Eleonora, Abbadessa, Giuliana, Giordano, Magalì, Grasso, Loredana, Borrione, Paolo, Racca, Silvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916624/ https://www.ncbi.nlm.nih.gov/pubmed/36763621 http://dx.doi.org/10.1371/journal.pone.0281718

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