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Reovirus Type 3 Dearing Variants Do Not Induce Necroptosis in RIPK3-Expressing Human Tumor Cell Lines

Reoviruses are used as oncolytic viruses to destroy tumor cells. The concomitant induction of anti-tumor immune responses enhances the efficacy of therapy in tumors with low amounts of immune infiltrates before treatment. The reoviruses should provoke immunogenic cell death (ICD) to stimulate a tumo...

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Detalles Bibliográficos
Autores principales: van den Wollenberg, Diana J. M., Kemp, Vera, Rabelink, Martijn J. W. E., Hoeben, Rob C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916669/
https://www.ncbi.nlm.nih.gov/pubmed/36768641
http://dx.doi.org/10.3390/ijms24032320