Cargando…

Deficiency of S100A9 Alleviates Sepsis-Induced Acute Liver Injury through Regulating AKT-AMPK-Dependent Mitochondrial Energy Metabolism

Acute liver injury (ALI) is recognized as a serious complication of sepsis in patients in intensive care units (ICUs). S100A8/A9 is known to promote inflammation and immune responses. However, the role of S100A8/A9 in the regulation of sepsis-induced ALI remains known. Our results indicated that S10...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yanting, Wu, Feng, Teng, Fei, Guo, Shubin, Li, Huihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916677/ https://www.ncbi.nlm.nih.gov/pubmed/36768433 http://dx.doi.org/10.3390/ijms24032112

Ejemplares similares

SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress
por: Zhang, Mengli, et al.
Publicado: (2019)

Portulaca oleracea alleviates CCl(4)-induced acute liver injury by regulating hepatic S100A8 and S100A9
por: Qian, Aruna, et al.
Publicado: (2022)

Ginsenoside Rg3 attenuates sepsis-induced injury and mitochondrial dysfunction in liver via AMPK-mediated autophagy flux
por: Xing, Wei, et al.
Publicado: (2017)

AMPK-Regulated and Akt-Dependent Enhancement of Glucose Uptake Is Essential in Ischemic Preconditioning-Alleviated Reperfusion Injury
por: Ji, Lele, et al.
Publicado: (2013)

Increased hepatic Akt phosphorylation alleviated glucose intolerance and improved liver function in leptin-deficient mice
por: Adar, Tomer, et al.
Publicado: (2023)

Paeoniflorin alleviates liver injury in hypercholesterolemic rats through the ROCK/AMPK pathway
por: Liu, Tong, et al.
Publicado: (2022)

S100A9 extends lifespan in insulin deficiency
por: Ramadori, Giorgio, et al.
Publicado: (2019)

Protective Role of AMPK against PINK1(B9) Flies' Neurodegeneration with Improved Mitochondrial Function
por: Xiang, Guoliang, et al.
Publicado: (2023)

LB100 ameliorates nonalcoholic fatty liver disease via the AMPK/Sirt1 pathway
por: Chen, Xue-Yang, et al.
Publicado: (2019)

Lactobacillus Strains Alleviated Hyperlipidemia and Liver Steatosis in Aging Rats via Activation of AMPK
por: Lew, Lee-Ching, et al.
Publicado: (2020)

SirT3 activates AMPK-related mitochondrial biogenesis and ameliorates sepsis-induced myocardial injury
por: Xin, Ting, et al.
Publicado: (2020)

GPR43 regulation of mitochondrial damage to alleviate inflammatory reaction in sepsis
por: Zhang, Weiwei, et al.
Publicado: (2021)

S100A8/A9 is the first predictive marker for neonatal sepsis
por: Pirr, Sabine, et al.
Publicado: (2021)

AMPK Activation Alleviates Myocardial Ischemia-Reperfusion Injury by Regulating Drp1-Mediated Mitochondrial Dynamics
por: Du, Jingxia, et al.
Publicado: (2022)

TRPM8 deficiency attenuates liver fibrosis through S100A9-HNF4α signaling
por: Liu, Qiang, et al.
Publicado: (2022)

Neuronal AMPK coordinates mitochondrial energy sensing and hypoxia resistance in C. elegans
por: Berry, Brandon J., et al.
Publicado: (2020)

Chloroquine increases phosphorylation of AMPK and Akt in myotubes
por: Spears, Larry D., et al.
Publicado: (2016)

Inhibition of aerobic glycolysis alleviates sepsis-induced acute kidney injury by promoting lactate/Sirtuin 3/AMPK-regulated autophagy
por: Tan, Chuyi, et al.
Publicado: (2021)

Cardiac Fibrosis Alleviated by Exercise Training Is AMPK-Dependent
por: Ma, Xiaowei, et al.
Publicado: (2015)

CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism
por: Xie, Tianqi, et al.
Publicado: (2020)

AMPK, a key regulator of metabolic/energy homeostasis and mitochondrial biogenesis in cancer cells
por: Chaube, B, et al.
Publicado: (2016)

S100a9 deficiency accelerates MDS-associated tumor escape via PD-1/PD-L1 overexpression: S100a9 deficiency accelerates tumor escape
por: Wang, Roujia, et al.
Publicado: (2023)

Metformin alleviates the calcification of aortic valve interstitial cells through activating the PI3K/AKT pathway in an AMPK dependent way
por: En, Qiao, et al.
Publicado: (2021)

Alisol A Alleviates Arterial Plaque by Activating AMPK/SIRT1 Signaling Pathway in apoE-Deficient Mice
por: Wang, Ke, et al.
Publicado: (2020)

Alleviation of sepsis-induced cardiac dysfunction by overexpression of Sestrin2 is associated with inhibition of p-S6K and activation of the p-AMPK pathway
por: Wang, Ziwen, et al.
Publicado: (2019)

Hypothalamic AMPK and energy balance
por: López, Miguel
Publicado: (2018)

Targeting USP9X–AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma
por: Zhang, Feng-Kun, et al.
Publicado: (2022)

IL-38 Alleviates Inflammation in Sepsis in Mice by Inhibiting Macrophage Apoptosis and Activation of the NLRP3 Inflammasome
por: Ge, Yun, et al.
Publicado: (2021)

Melatonin Alleviates Cardiac Function in Sepsis-Caused Myocarditis via Maintenance of Mitochondrial Function
por: Chen, Liyang, et al.
Publicado: (2021)

Intracellular S100A9 Promotes Myeloid-Derived Suppressor Cells during Late Sepsis
por: Dai, Jun, et al.
Publicado: (2017)

Targeting S100A9 Reduces Neutrophil Recruitment, Inflammation and Lung Damage in Abdominal Sepsis
por: Ding, Zhiyi, et al.
Publicado: (2021)

Mitochondrial Methionyl-tRNA Formyltransferase Deficiency Alleviates Metaflammation by Modulating Mitochondrial Activity in Mice
por: Sun, Xiaoxiao, et al.
Publicado: (2023)

AMPK-PINK1/Parkin Mediated Mitophagy Is Necessary for Alleviating Oxidative Stress-Induced Intestinal Epithelial Barrier Damage and Mitochondrial Energy Metabolism Dysfunction in IPEC-J2
por: Cao, Shuting, et al.
Publicado: (2021)

AMPK, Mitochondrial Function, and Cardiovascular Disease
por: Wu, Shengnan, et al.
Publicado: (2020)

Oleuropein alleviates gestational diabetes mellitus by activating AMPK signaling
por: Zhang, Zhiwei, et al.
Publicado: (2020)

c-Myc and AMPK Control Cellular Energy Levels by Cooperatively Regulating Mitochondrial Structure and Function
por: Edmunds, Lia R., et al.
Publicado: (2015)

Influences of S100A8 and S100A9 on Proliferation of Nasopharyngeal Carcinoma Cells through PI3K/Akt Signaling Pathway
por: Wen, Liting, et al.
Publicado: (2021)

ALLEVIATING LONELINESS AT 100: IS RELIGION A SOLUTION?
por: Bishop, Alex J, et al.
Publicado: (2019)

Quercetin Alleviates Inflammation and Energy Deficiency Induced by Lipopolysaccharide in Chicken Embryos
por: Yu, Jinhai, et al.
Publicado: (2023)

Metformin alleviates lead-induced mitochondrial fragmentation via AMPK/Nrf2 activation in SH-SY5Y cells
por: Yang, Luoyao, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_56kia0i1q72j15l6it2si9ajae