Cargando…

Ca(2+)-Permeable AMPA Receptors Contribute to Changed Dorsal Horn Neuronal Firing and Inflammatory Pain

The dorsal horn (DH) neurons of the spinal cord play a critical role in nociceptive input integration and processing in the central nervous system. Engaged neuronal classes and cell-specific excitability shape nociceptive computation within the DH. The DH hyperexcitability (central sensitisation) ha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kopach, Olga, Dobropolska, Yulia, Belan, Pavel, Voitenko, Nana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916706/ https://www.ncbi.nlm.nih.gov/pubmed/36768663 http://dx.doi.org/10.3390/ijms24032341

Ejemplares similares

Development of inflammation-induced hyperalgesia and allodynia is associated with the upregulation of extrasynaptic AMPA receptors in tonically firing lamina II dorsal horn neurons
por: Kopach, Olga, et al.
Publicado: (2012)

Inhibition of Spinal Ca(2+)-Permeable AMPA Receptors with Dicationic Compounds Alleviates Persistent Inflammatory Pain without Adverse Effects
por: Kopach, Olga, et al.
Publicado: (2016)

Spinal AMPA receptors: Amenable players in central sensitization for chronic pain therapy?
por: Kopach, Olga, et al.
Publicado: (2021)

Opposite, bidirectional shifts in excitation and inhibition in specific types of dorsal horn interneurons are associated with spasticity and pain post-SCI
por: Kopach, Olga, et al.
Publicado: (2017)

Functional Characterization of Lamina X Neurons in ex-Vivo Spinal Cord Preparation
por: Krotov, Volodymyr, et al.
Publicado: (2017)

Diabetes-Induced Amplification of Nociceptive DRG Neuron Output by Upregulation of Somatic T-Type Ca(2+) Channels
por: Ivasiuk, Arsentii, et al.
Publicado: (2023)

Peripheral Inflammation Results in Increased Excitability of Capsaicin-Insensitive Nociceptive DRG Neurons Mediated by Upregulation of ASICs and Voltage-Gated Ion Channels
por: Duzhyy, Dmytro E., et al.
Publicado: (2021)

Synchronous firing of dorsal horn neurons at the origin of dorsal root reflexes in naïve and paw-inflamed mice
por: Lucas-Romero, Javier, et al.
Publicado: (2022)

Trigeminal Medullary Dorsal Horn Neurons Activated by Nasal Stimulation Coexpress AMPA, NMDA, and NK1 Receptors
por: McCulloch, P. F., et al.
Publicado: (2013)

Upregulation of T-type Ca(2+) channels in long-term diabetes determines increased excitability of a specific type of capsaicin-insensitive DRG neurons
por: Duzhyy, Dmytro E, et al.
Publicado: (2015)

Nociceptive Neurons Differentially Express Fast and Slow T-Type Ca(2+) Currents in Different Types of Diabetic Neuropathy
por: Khomula, Eugen V., et al.
Publicado: (2014)

Enhancement by interleukin-1β of AMPA and NMDA receptor-mediated currents in adult rat spinal superficial dorsal horn neurons
por: Liu, Tao, et al.
Publicado: (2013)

Expression of AMPA receptor subunits at synapses in laminae I–III of the rodent spinal dorsal horn
por: Polgár, Erika, et al.
Publicado: (2008)

Ca(2+) Permeable AMPA Channels in Diseases of the Nervous System
por: Weiss, John H.
Publicado: (2011)

Ca(2+)-permeable AMPA receptors in homeostatic synaptic plasticity
por: Lee, Hey-Kyoung
Publicado: (2012)

Sensory neuron–derived Na(V)1.7 contributes to dorsal horn neuron excitability
por: Alles, Sascha R. A., et al.
Publicado: (2020)

Phorbol Ester Modulation of Ca(2+) Channels Mediates Nociceptive Transmission in Dorsal Horn Neurones
por: Yang, Li, et al.
Publicado: (2013)

Ca(2+)-permeable AMPA receptors in mouse olfactory bulb astrocytes
por: Droste, Damian, et al.
Publicado: (2017)

Optimized Model of Cerebral Ischemia In situ for the Long-Lasting Assessment of Hippocampal Cell Death
por: Rybachuk, Oksana, et al.
Publicado: (2017)

Expression of cholecystokinin by neurons in mouse spinal dorsal horn
por: Gutierrez‐Mecinas, Maria, et al.
Publicado: (2019)

Crosstalk between Activated Microglia and Neurons in the Spinal Dorsal Horn Contributes to Stress-induced Hyperalgesia
por: Qi, Jian, et al.
Publicado: (2016)

Ca(2+)‐permeable AMPA receptors and their auxiliary subunits in synaptic plasticity and disease
por: Cull‐Candy, Stuart G., et al.
Publicado: (2021)

Ketamine’s rapid antidepressant effects are mediated by Ca(2+)-permeable AMPA receptors
por: Zaytseva, Anastasiya, et al.
Publicado: (2023)

Pain-related synaptic plasticity in spinal dorsal horn neurons: role of CGRP
por: Bird, Gary C, et al.
Publicado: (2006)

Tranexamic acid evokes pain by modulating neuronal excitability in the spinal dorsal horn
por: Ohashi, Nobuko, et al.
Publicado: (2015)

Near-Infrared Photobiomodulation of the Peripheral Nerve Inhibits the Neuronal Firing in a Rat Spinal Dorsal Horn Evoked by Mechanical Stimulation
por: Uta, Daisuke, et al.
Publicado: (2023)

Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons
por: Suyama, Shigetomo, et al.
Publicado: (2017)

Properties of GABAergic Neurons Containing Calcium-Permeable Kainate and AMPA-Receptors
por: Zinchenko, Valery Petrovich, et al.
Publicado: (2021)

Nano-engineered microcapsules boost the treatment of persistent pain
por: Kopach, Olga, et al.
Publicado: (2018)

Contribution of dorsal horn CGRP-expressing interneurons to mechanical sensitivity
por: Löken, Line S, et al.
Publicado: (2021)

Different Mechanisms of Ca(2+) Transport in NMDA and Ca(2+)-permeable AMPA Glutamate Receptor Channels
por: Wollmuth, Lonnie P., et al.
Publicado: (1998)

TARP γ-2 Is Required for Inflammation-Associated AMPA Receptor Plasticity within Lamina II of the Spinal Cord Dorsal Horn
por: Sullivan, Steve J., et al.
Publicado: (2017)

Neuronal P2X4 receptor may contribute to peripheral inflammatory pain in rat spinal dorsal horn
por: Ducza, László, et al.
Publicado: (2023)

Spinal PKCα inhibition and gene-silencing for pain relief: AMPAR trafficking at the synapses between primary afferents and sensory interneurons
por: Kopach, Olga, et al.
Publicado: (2018)

Recent advances in our understanding of the organization of dorsal horn neuron populations and their contribution to cutaneous mechanical allodynia
por: Peirs, Cedric, et al.
Publicado: (2020)

Reducing Auditory Nerve Excitability by Acute Antagonism of Ca(2+)-Permeable AMPA Receptors
por: Walia, Amit, et al.
Publicado: (2021)

Calcium-Permeable AMPA Receptors in the Retina
por: Diamond, Jeffrey S.
Publicado: (2011)

Segmental and descending control of primary afferent input to the spinal lamina X
por: Krotov, Volodymyr, et al.
Publicado: (2022)

Long-term actions of interleukin-1β on delay and tonic firing neurons in rat superficial dorsal horn and their relevance to central sensitization
por: Gustafson-Vickers, Sabrina L, et al.
Publicado: (2008)

Relationship between Laser Intensity at the Peripheral Nerve and Inhibitory Effect of Percutaneous Photobiomodulation on Neuronal Firing in a Rat Spinal Dorsal Horn
por: Uta, Daisuke, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6elf7ebba2c79qbn46jbo58r58