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N-Doped Carbon/CeO(2) Composite as a Biomimetic Catalyst for Antibacterial Application
Exploring new and high efficiency mimic enzymes is a vital and novel strategy for antibacterial application. Haloperoxidase-like enzymes have attracted wide attention thanks to their amazing catalytic property for hypohalous acid generation from hydrogen peroxide and halides. However, few materials...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916758/ https://www.ncbi.nlm.nih.gov/pubmed/36768764 http://dx.doi.org/10.3390/ijms24032445 |
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author | Wang, Nan Zhai, Xiaofan Guan, Fang Zhang, Ruiyong Hou, Baorong Duan, Jizhou |
author_facet | Wang, Nan Zhai, Xiaofan Guan, Fang Zhang, Ruiyong Hou, Baorong Duan, Jizhou |
author_sort | Wang, Nan |
collection | PubMed |
description | Exploring new and high efficiency mimic enzymes is a vital and novel strategy for antibacterial application. Haloperoxidase-like enzymes have attracted wide attention thanks to their amazing catalytic property for hypohalous acid generation from hydrogen peroxide and halides. However, few materials have displayed halogenating catalytic performance until now. Herein, we synthesized N-doped C/CeO(2) (N-C/CeO(2)) composite materials by a combination of the liquid and solid-state method. N-C/CeO(2) can possess haloperoxidase-like catalytic activity by catalyzing the bromination of organic signaling compounds (phenol red) with H(2)O(2) at a wide range of temperatures (20 °C to 55 °C), with a solution color changing from yellow to blue. Meanwhile, it exhibits high catalytic stability/recyclability in the catalytic reaction. The synthesized N-C/CeO(2) composite can effectively catalyze the oxidation of Br(−) with H(2)O(2) to produce HBrO without the presence of phenol red. The produced HBrO can resist typical marine bacteria like Pseudomonas aeruginosa. This study provides an efficient biomimetic haloperoxidase and a novel sustainable method for antibacterial application. |
format | Online Article Text |
id | pubmed-9916758 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99167582023-02-11 N-Doped Carbon/CeO(2) Composite as a Biomimetic Catalyst for Antibacterial Application Wang, Nan Zhai, Xiaofan Guan, Fang Zhang, Ruiyong Hou, Baorong Duan, Jizhou Int J Mol Sci Article Exploring new and high efficiency mimic enzymes is a vital and novel strategy for antibacterial application. Haloperoxidase-like enzymes have attracted wide attention thanks to their amazing catalytic property for hypohalous acid generation from hydrogen peroxide and halides. However, few materials have displayed halogenating catalytic performance until now. Herein, we synthesized N-doped C/CeO(2) (N-C/CeO(2)) composite materials by a combination of the liquid and solid-state method. N-C/CeO(2) can possess haloperoxidase-like catalytic activity by catalyzing the bromination of organic signaling compounds (phenol red) with H(2)O(2) at a wide range of temperatures (20 °C to 55 °C), with a solution color changing from yellow to blue. Meanwhile, it exhibits high catalytic stability/recyclability in the catalytic reaction. The synthesized N-C/CeO(2) composite can effectively catalyze the oxidation of Br(−) with H(2)O(2) to produce HBrO without the presence of phenol red. The produced HBrO can resist typical marine bacteria like Pseudomonas aeruginosa. This study provides an efficient biomimetic haloperoxidase and a novel sustainable method for antibacterial application. MDPI 2023-01-26 /pmc/articles/PMC9916758/ /pubmed/36768764 http://dx.doi.org/10.3390/ijms24032445 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Wang, Nan Zhai, Xiaofan Guan, Fang Zhang, Ruiyong Hou, Baorong Duan, Jizhou N-Doped Carbon/CeO(2) Composite as a Biomimetic Catalyst for Antibacterial Application |
title | N-Doped Carbon/CeO(2) Composite as a Biomimetic Catalyst for Antibacterial Application |
title_full | N-Doped Carbon/CeO(2) Composite as a Biomimetic Catalyst for Antibacterial Application |
title_fullStr | N-Doped Carbon/CeO(2) Composite as a Biomimetic Catalyst for Antibacterial Application |
title_full_unstemmed | N-Doped Carbon/CeO(2) Composite as a Biomimetic Catalyst for Antibacterial Application |
title_short | N-Doped Carbon/CeO(2) Composite as a Biomimetic Catalyst for Antibacterial Application |
title_sort | n-doped carbon/ceo(2) composite as a biomimetic catalyst for antibacterial application |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916758/ https://www.ncbi.nlm.nih.gov/pubmed/36768764 http://dx.doi.org/10.3390/ijms24032445 |
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