Extracellular Vesicle-microRNAs as Diagnostic Biomarkers in Preterm Neonates

Neonates born prematurely (<37 weeks of gestation) are at a significantly increased risk of developing inflammatory conditions associated with high mortality rates, including necrotizing enterocolitis, bronchopulmonary dysplasia, and hypoxic-ischemic brain damage. Recently, research has focused o...

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Autores principales: Schiller, Emily A., Cohen, Koral, Lin, Xinhua, El-Khawam, Rania, Hanna, Nazeeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916767/
https://www.ncbi.nlm.nih.gov/pubmed/36768944
http://dx.doi.org/10.3390/ijms24032622
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author Schiller, Emily A.
Cohen, Koral
Lin, Xinhua
El-Khawam, Rania
Hanna, Nazeeh
author_facet Schiller, Emily A.
Cohen, Koral
Lin, Xinhua
El-Khawam, Rania
Hanna, Nazeeh
author_sort Schiller, Emily A.
collection PubMed
description Neonates born prematurely (<37 weeks of gestation) are at a significantly increased risk of developing inflammatory conditions associated with high mortality rates, including necrotizing enterocolitis, bronchopulmonary dysplasia, and hypoxic-ischemic brain damage. Recently, research has focused on characterizing the content of extracellular vesicles (EVs), particularly microRNAs (miRNAs), for diagnostic use. Here, we describe the most recent work on EVs-miRNAs biomarkers discovery for conditions that commonly affect premature neonates.
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spelling pubmed-99167672023-02-11 Extracellular Vesicle-microRNAs as Diagnostic Biomarkers in Preterm Neonates Schiller, Emily A. Cohen, Koral Lin, Xinhua El-Khawam, Rania Hanna, Nazeeh Int J Mol Sci Review Neonates born prematurely (<37 weeks of gestation) are at a significantly increased risk of developing inflammatory conditions associated with high mortality rates, including necrotizing enterocolitis, bronchopulmonary dysplasia, and hypoxic-ischemic brain damage. Recently, research has focused on characterizing the content of extracellular vesicles (EVs), particularly microRNAs (miRNAs), for diagnostic use. Here, we describe the most recent work on EVs-miRNAs biomarkers discovery for conditions that commonly affect premature neonates. MDPI 2023-01-30 /pmc/articles/PMC9916767/ /pubmed/36768944 http://dx.doi.org/10.3390/ijms24032622 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Schiller, Emily A.
Cohen, Koral
Lin, Xinhua
El-Khawam, Rania
Hanna, Nazeeh
Extracellular Vesicle-microRNAs as Diagnostic Biomarkers in Preterm Neonates
title Extracellular Vesicle-microRNAs as Diagnostic Biomarkers in Preterm Neonates
title_full Extracellular Vesicle-microRNAs as Diagnostic Biomarkers in Preterm Neonates
title_fullStr Extracellular Vesicle-microRNAs as Diagnostic Biomarkers in Preterm Neonates
title_full_unstemmed Extracellular Vesicle-microRNAs as Diagnostic Biomarkers in Preterm Neonates
title_short Extracellular Vesicle-microRNAs as Diagnostic Biomarkers in Preterm Neonates
title_sort extracellular vesicle-micrornas as diagnostic biomarkers in preterm neonates
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916767/
https://www.ncbi.nlm.nih.gov/pubmed/36768944
http://dx.doi.org/10.3390/ijms24032622
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AT elkhawamrania extracellularvesiclemicrornasasdiagnosticbiomarkersinpretermneonates
AT hannanazeeh extracellularvesiclemicrornasasdiagnosticbiomarkersinpretermneonates

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