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CD47-Dependent Regulation of Immune Checkpoint Gene Expression and MYCN mRNA Splicing in Murine CD8 and Jurkat T Cells

Elevated expression of CD47 in some cancers is associated with poor survival related to its function as an innate immune checkpoint when expressed on tumor cells. In contrast, elevated CD47 expression in cutaneous melanomas is associated with improved survival. Previous studies implicated protective...

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Detalles Bibliográficos
Autores principales: Kaur, Sukhbir, Awad, Duha, Finney, Richard P., Meyer, Thomas J., Singh, Satya P., Cam, Margaret C., Karim, Baktiar O., Warner, Andrew C., Roberts, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916813/
https://www.ncbi.nlm.nih.gov/pubmed/36768931
http://dx.doi.org/10.3390/ijms24032612