The COPD-Associated Polymorphism Impairs the CFTR Function to Suppress Excessive IL-8 Production upon Environmental Pathogen Exposure

COPD is a lifestyle-related disease resulting from irreversible damage to respiratory tissues mostly due to chronic exposure to environmental pollutants, including cigarette smoke. Environmental pathogens and pollutants induce the acquired dysfunction of the CFTR Cl(−) channel, which is invoked in C...

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Detalles Bibliográficos
Autores principales: Hinata, Daichi, Fukuda, Ryosuke, Okiyoneda, Tsukasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916815/
https://www.ncbi.nlm.nih.gov/pubmed/36768629
http://dx.doi.org/10.3390/ijms24032305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916815/
https://www.ncbi.nlm.nih.gov/pubmed/36768629
http://dx.doi.org/10.3390/ijms24032305

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