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Cytochrome P450 1B1 Expression Regulates Intracellular Iron Levels and Oxidative Stress in the Retinal Endothelium

Cytochrome P450 (CYP) 1B1 is a heme-containing monooxygenase found mainly in extrahepatic tissues, including the retina. CYP1B1 substrates include exogenous aromatic hydrocarbons, such as dioxins, and endogenous bioactive compounds, including 17β-estradiol (E2) and arachidonic acid. The endogenous c...

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Detalles Bibliográficos
Autores principales:	Song, Yong-Seok, Zaitoun, Ismail S., Wang, Shoujian, Darjatmoko, Soesiawati R., Sorenson, Christine M., Sheibani, Nader
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916835/ https://www.ncbi.nlm.nih.gov/pubmed/36768740 http://dx.doi.org/10.3390/ijms24032420

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