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Association of High LAT1 Expression with Poor Prognosis and Recurrence in Colorectal Cancer Patients Treated with Oxaliplatin-Based Adjuvant Chemotherapy

The mammalian target of rapamycin (mTOR) is often activated in several cancers. We focused on two mTOR regulatory mechanisms: oxaliplatin-induced mTOR signaling and L-type amino acid transporter 1 (LAT1)-induced mTOR activation. High LAT1 expression in several cancers is associated with mTOR activat...

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Detalles Bibliográficos
Autores principales:	Shibasaki, Yuta, Yokobori, Takehiko, Sohda, Makoto, Shioi, Ikuma, Ozawa, Naoya, Komine, Chika, Suga, Kunihiko, Nakazawa, Nobuhiro, Osone, Katsuya, Shiraishi, Takuya, Okada, Takuhisa, Sano, Akihiko, Sakai, Makoto, Ogawa, Hiroomi, Kaira, Kyoichi, Shirabe, Ken, Saeki, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916902/ https://www.ncbi.nlm.nih.gov/pubmed/36768934 http://dx.doi.org/10.3390/ijms24032604

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