Na, K-ATPase α1 cooperates with its endogenous ligand to reprogram immune microenvironment of lung carcinoma and promotes immune escape

Dysregulated endocrine hormones (EHs) contribute to tumorigenesis, but how EHs affect the tumor immune microenvironment (TIM) and the immunotherapy of non–small cell lung cancer (NSCLC) is still unclear. Here, endogenous ouabain (EO), an adrenergic hormone, is elevated in patients with NSCLC and clo...

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Detalles Bibliográficos
Autores principales: Yang, Kaiyong, Li, Zijian, Chen, Yan, Yin, Fangzhou, Ji, Xiaojun, Zhou, Jiaqian, Li, Xin, Zeng, Tao, Fei, Chenghao, Ren, Chenchen, Wang, Yulin, Fang, Lei, Chen, Lili, Zhang, Pei, Mu, Liyan, Qian, Yuxuan, Yin, Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916986/
https://www.ncbi.nlm.nih.gov/pubmed/36763655
http://dx.doi.org/10.1126/sciadv.ade5393

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