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The Integrator complex regulates microRNA abundance through RISC loading

MicroRNA (miRNA) homeostasis is crucial for the posttranscriptional regulation of their target genes during development and in disease states. miRNAs are derived from primary transcripts and are processed from a hairpin precursor intermediary to a mature 22-nucleotide duplex RNA. Loading of the dupl...

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Detalles Bibliográficos
Autores principales:	Kirstein, Nina, Dokaneheifard, Sadat, Cingaram, Pradeep Reddy, Valencia, Monica Guiselle, Beckedorff, Felipe, Gomes Dos Santos, Helena, Blumenthal, Ezra, Tayari, Mina Masoumeh, Gaidosh, Gabriel Stephen, Shiekhattar, Ramin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916992/ https://www.ncbi.nlm.nih.gov/pubmed/36763664 http://dx.doi.org/10.1126/sciadv.adf0597

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